HitPredict

Interactor 1: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Interactor 2: RBAK (Q9NYW8)
RB-associated KRAB zinc finger protein (RB-associated KRAB repressor) (hRBaK) (Zinc finger protein 769)
Gene: RBAK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, 31403225
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 714
+	Hs
		983755 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF91_HUMAN (49-702): 0: 850: 39.70
+	Hs
		64140 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN729_HUMAN (49-688): 0: 776: 36.90
+	Hs
		64135 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN729_HUMAN (49-688): 0: 776: 36.90
+	Hs
		1027102 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN227_HUMAN (74-677): 0: 682: 40.98
+	Hs
		800447 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN227_HUMAN (74-677): 0: 682: 40.98
+	Hs
		67424 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN850_HUMAN (49-561): 0: 616: 37.09
+	Hs
		1027126 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN615_HUMAN (272-713): 0: 610: 50.45
+	Hs
		1027081 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN534_HUMAN (167-712): 0: 607: 43.27
+	Hs
		800409 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZN569_HUMAN (179-713): 0: 647: 45.73
+	Hs
		1027143 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN420_HUMAN (326-714): 0: 590: 56.01
+	Hs
		970657 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZNF45_HUMAN (56-508): 0: 560: 37.36
+	Hs
		1027116 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN567_HUMAN (5-648): 2.2e-180: 530: 47.94
+	Hs
		800350 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		ZNF45_HUMAN (56-508): 0: 560: 37.36
+	Hs
		1027217 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN184_HUMAN (482-713): 6.18e-116: 367: 48.29
+	Hs
		800425 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		Z585A_HUMAN (397-714): 1.07e-117: 372: 44.06
+	Hs
		1027345 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN337_HUMAN (506-713): 9.19e-67: 236: 41.83
+	Hs
		1027211 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN607_HUMAN (135-452): 4.57e-59: 213: 37.95
+	Hs
		1027294 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN226_HUMAN (49-183): 3.03e-22: 104: 12.59
+	Hs
		988824 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		ZN33A_HUMAN (458-713): 3.84e-17: 87.8: 25.78
+	Hs
		800406 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		Z585B_HUMAN (49-157): 4.65e-17: 87.4: 8.26