HitPredict

Interactor 1: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Interactor 2: RASF1 (Q9NS23)
Ras association domain-containing protein 1
Gene: RASSF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 14729613, 26186194, 24366813, 28514442, 28205554, 32296183, 24981860, 33961781, 17379520, 17598981, 20086174, 32707033, 36736316, 17889669, 24255178, 23455922, 18347058, unassigned1304, 20920251
Identification Methods two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification and 1 others

more...
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mst1_SARAH~Nore1-SARAH, C1_1~Pkinase, Nore1-SARAH~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0050821 - protein stabilization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 491
Hs

1 344
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024