Protein: DDX5
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)

Gene: DDX5
Organism: Homo sapiens
Interactions: 484
UniProt ID: P17844

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

608686

DDX17
Probable ATP-dependent RNA helicase DDX17

13

9

Small-scale

0.979

High

608766

RNC
Ribonuclease 3

5

7

Small-scale

0.919

High

285069

EED
Polycomb protein EED

3

18

Small-scale

0.827

High

608596

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

3

5

Small-scale

0.827

High

608558

DHX9
ATP-dependent RNA helicase A

2

10

High-throughput

0.806

High

608507

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

2

12

Small-scale

0.789

High

608548

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

4

High-throughput

0.789

High

608709

RANB9
Ran-binding protein 9

2

4

Small-scale

0.789

High

608565

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

10

Small-scale

0.776

High

141315

DDX3X
ATP-dependent RNA helicase DDX3X

2

12

Small-scale

0.770

High

608440

DDX5
Probable ATP-dependent RNA helicase DDX5

2

8

Small-scale

0.754

High

608749

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

2

14

Small-scale

0.754

High

413148

P53
Cellular tumor antigen p53

8

3

Small-scale

0.748

High

345343

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

11

Small-scale

0.737

High

395450

ESR1
Estrogen receptor

6

20

Small-scale

0.728

High

484903

ROA1
Heterogeneous nuclear ribonucleoprotein A1

6

10

Small-scale

0.726

High

608584

HDAC1
Histone deacetylase 1

5

12

Small-scale

0.709

High

608562

EP300
Histone acetyltransferase p300

4

9

Small-scale

0.702

High

608513

DAPK1
Death-associated protein kinase 1

1

1

High-throughput

0.691

High

608540

RBM6
RNA-binding protein 6

1

13

High-throughput

0.691

High

608566

ILF3
Interleukin enhancer-binding factor 3

1

10

High-throughput

0.691

High

608578

ILK
Scaffold protein ILK

1

2

High-throughput

0.691

High

608762

DDX21
Nucleolar RNA helicase 2

1

12

High-throughput

0.691

High

608475

FUS
RNA-binding protein FUS

4

17

High-throughput

0.683

High

608617

EZH2
Histone-lysine N-methyltransferase EZH2

4

8

Small-scale

0.683

High

240691

PRKN
E3 ubiquitin-protein ligase parkin

4

11

High-throughput

0.676

High

371104

MYC
Myc proto-oncogene protein

4

8

Small-scale

0.676

High

608467

HNRH1
Heterogeneous nuclear ribonucleoprotein H

3

13

High-throughput

0.664

High

608455

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

3

Small-scale

0.662

High

608546

RBM10
RNA-binding protein 10

1

9

High-throughput

0.656

High

182906

NKRF
NF-kappa-B-repressing factor

1

0

High-throughput

0.656

High

608485

MATR3
Matrin-3

3

4

High-throughput

0.656

High

608605

SUZ12
Polycomb protein SUZ12

3

1

Small-scale

0.650

High

185413

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

7

High-throughput

0.647

High

464795

SP1
Transcription factor Sp1

2

1

Small-scale

0.646

High

608505

CDK9
Cyclin-dependent kinase 9

3

8

Small-scale

0.640

High

608575

TIF1B
Transcription intermediary factor 1-beta

3

12

Small-scale

0.640

High

608680

HDAC2
Histone deacetylase 2

3

12

Small-scale

0.640

High

362731

EGFR
Epidermal growth factor receptor

3

3

High-throughput

0.633

High

608710

SRPK1
SRSF protein kinase 1

2

10

High-throughput

0.628

High

315091

RECQ4
ATP-dependent DNA helicase Q4

1

17

High-throughput

0.618

High

608443

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

High-throughput

0.618

High

608444

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

Small-scale

0.618

High

608469

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.618

High

608518

FBXW4
F-box/WD repeat-containing protein 4

1

15

Small-scale

0.618

High

608543

RED1
Double-stranded RNA-specific editase 1

1

10

High-throughput

0.618

High

608555

ERCC6
DNA excision repair protein ERCC-6

1

18

Small-scale

0.618

High

608592

DX39B
Spliceosome RNA helicase DDX39B

1

14

Small-scale

0.618

High

608601

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.618

High

608613

TRIP4
Activating signal cointegrator 1

1

1

High-throughput

0.618

High

608632

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.618

High

608638

PRP8
Pre-mRNA-processing-splicing factor 8

1

3

High-throughput

0.618

High

608641

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

608663

CMTR1
Cap-specific mRNA

1

2

High-throughput

0.618

High

608675

DGCR8
Microprocessor complex subunit DGCR8

1

2

Small-scale

0.618

High

608692

IGSF8
Immunoglobulin superfamily member 8

1

8

High-throughput

0.618

High

608695

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

11

High-throughput

0.618

High

608705

ODAD4
Outer dynein arm-docking complex subunit 4

1

7

High-throughput

0.618

High

608724

MEP50
Methylosome protein WDR77

1

11

High-throughput

0.618

High

608729

DDX23
Probable ATP-dependent RNA helicase DDX23

1

17

High-throughput

0.618

High

608795

FBW1A
F-box/WD repeat-containing protein 1A

1

11

High-throughput

0.618

High

462236

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

9

High-throughput

0.611

High

480028

RU1C
U1 small nuclear ribonucleoprotein C

2

3

High-throughput

0.611

High

521194

ARAF
Serine/threonine-protein kinase A-Raf

2

3

High-throughput

0.611

High

608478

RBMX
RNA-binding motif protein, X chromosome

2

12

High-throughput

0.611

High

608588

CUL3
Cullin-3

2

16

High-throughput

0.611

High

608589

CUL4A
Cullin-4A

2

16

High-throughput

0.611

High

608590

CUL4B
Cullin-4B

2

16

High-throughput

0.611

High

608597

RBM39
RNA-binding protein 39

2

11

High-throughput

0.611

High

608614

ELAV1
ELAV-like protein 1

2

5

High-throughput

0.611

High

608619

CDC37
Hsp90 co-chaperone Cdc37

2

3

Small-scale

0.611

High

608752

RMD5A
E3 ubiquitin-protein transferase RMND5A

2

3

High-throughput

0.611

High

608781

IPO11
Importin-11

2

7

High-throughput

0.611

High

608544

SMAD3
Mothers against decapentaplegic homolog 3

2

10

Small-scale

0.602

High

231099

AIRE
Autoimmune regulator

2

18

Small-scale

0.601

High

541815

TOP1
DNA topoisomerase 1

2

3

Small-scale

0.601

High

608472

CTNB1
Catenin beta-1

2

4

Small-scale

0.601

High

608571

TADBP
TAR DNA-binding protein 43

2

10

High-throughput

0.601

High

608552

EXOSX
Exosome complex component 10

1

0

Small-scale

0.586

High

131719

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

6

Small-scale

0.584

High

188164

HDAC3
Histone deacetylase 3

2

9

Small-scale

0.584

High

587869

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

608461

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.584

High

608474

RFA3
Replication protein A 14 kDa subunit

2

4

High-throughput

0.584

High

608480

VHL
von Hippel-Lindau disease tumor suppressor

2

3

Small-scale

0.584

High

608503

GSK3B
Glycogen synthase kinase-3 beta

2

10

High-throughput

0.584

High

608564

TFCP2
Alpha-globin transcription factor CP2

2

2

High-throughput

0.584

High

608567

NFX1
Transcriptional repressor NF-X1

2

7

Small-scale

0.584

High

608609

PCBP1
Poly(rC)-binding protein 1

2

11

Small-scale

0.584

High

608624

LARP7
La-related protein 7

2

17

High-throughput

0.584

High

608646

MEPCE
7SK snRNA methylphosphate capping enzyme

2

4

High-throughput

0.584

High

608698

AURKB
Aurora kinase B

2

8

High-throughput

0.584

High

608714

RING2
E3 ubiquitin-protein ligase RING2

2

10

Small-scale

0.584

High

608761

ANLN
Anillin

2

3

High-throughput

0.584

High

608777

KS6B2
Ribosomal protein S6 kinase beta-2

2

5

Small-scale

0.584

High

608778

NXF1
Nuclear RNA export factor 1

2

2

Small-scale

0.584

High

608561

NCBP1
Nuclear cap-binding protein subunit 1

1

2

High-throughput

0.575

High

608627

Q5RI18
Heterogeneous nuclear ribonucleoprotein U

1

4

High-throughput

0.575

High

608782

DDX41
Probable ATP-dependent RNA helicase DDX41

1

14

High-throughput

0.575

High

608792

DICER
Endoribonuclease Dicer

1

14

Small-scale

0.575

High

563146

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

High-throughput

0.571

High

608441

VCAM1
Vascular cell adhesion protein 1

2

3

High-throughput

0.571

High

608457

TYY1
Transcriptional repressor protein YY1

2

6

Small-scale

0.571

High

608516

TERA
Transitional endoplasmic reticulum ATPase

2

3

High-throughput

0.571

High

608593

PTK6
Protein-tyrosine kinase 6

2

2

High-throughput

0.571

High

608599

RRP1B
Ribosomal RNA processing protein 1 homolog B

2

4

High-throughput

0.571

High

608748

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

2

15

Small-scale

0.571

High

608779

DUX4
Double homeobox protein 4

1

9

High-throughput

0.569

High

297444

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

Small-scale

0.561

High

608496

MAPK2
MAP kinase-activated protein kinase 2

1

2

Small-scale

0.561

High

608510

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.554

High

608615

SMAD1
Mothers against decapentaplegic homolog 1

1

10

Small-scale

0.554

High

608788

HECD1
E3 ubiquitin-protein ligase HECTD1

1

9

High-throughput

0.553

High

529029

TAU
Microtubule-associated protein tau

2

10

High-throughput

0.552

High

608448

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.549

High

608458

PSA3
Proteasome subunit alpha type-3

1

0

Small-scale

0.537

High

130371

SPT5H
Transcription elongation factor SPT5

1

6

High-throughput

0.536

High

172012

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

10

High-throughput

0.536

High

214697

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

3

High-throughput

0.536

High

245196

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

7

High-throughput

0.536

High

271411

ATG13
Autophagy-related protein 13

1

1

High-throughput

0.536

High

272612

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

7

High-throughput

0.536

High

285800

SF3B1
Splicing factor 3B subunit 1

1

2

High-throughput

0.536

High

362152

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.536

High

477911

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

574136

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

576276

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

7

High-throughput

0.536

High

608445

TBP
TATA-box-binding protein

1

1

Small-scale

0.536

High

608449

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

9

High-throughput

0.536

High

608460

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

608464

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

7

High-throughput

0.536

High

608465

AKT1
RAC-alpha serine/threonine-protein kinase

1

9

Small-scale

0.536

High

608470

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

608492

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

608497

CENPA
Histone H3-like centromeric protein A

1

8

Small-scale

0.536

High

608511

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

10

High-throughput

0.536

High

608528

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

608530

RUXF
Small nuclear ribonucleoprotein F

1

4

High-throughput

0.536

High

608542

SRPK2
SRSF protein kinase 2

1

11

High-throughput

0.536

High

608560

SSRP1
FACT complex subunit SSRP1

1

9

High-throughput

0.536

High

608576

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.536

High

608580

TNK1
Non-receptor tyrosine-protein kinase TNK1

1

5

High-throughput

0.536

High

608586

CUL1
Cullin-1

1

16

High-throughput

0.536

High

608587

CUL2
Cullin-2

1

16

High-throughput

0.536

High

608591

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.536

High

608611

SF3A1
Splicing factor 3A subunit 1

1

2

High-throughput

0.536

High

608616

NEDD8
Ubiquitin-like protein NEDD8

1

4

High-throughput

0.536

High

608620

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

8

High-throughput

0.536

High

608626

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.536

High

608643

HAKAI
E3 ubiquitin-protein ligase Hakai

1

8

Small-scale

0.536

High

608647

CSN6
COP9 signalosome complex subunit 6

1

5

High-throughput

0.536

High

608648

MAEA
E3 ubiquitin-protein transferase MAEA

1

3

High-throughput

0.536

High

608649

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

6

High-throughput

0.536

High

608654

ZCH18
Zinc finger CCCH domain-containing protein 18

1

4

High-throughput

0.536

High

608655

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

608656

RBM45
RNA-binding protein 45

1

11

High-throughput

0.536

High

608657

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.536

High

608658

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

3

High-throughput

0.536

High

608667

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.536

High

608674

PSPC1
Paraspeckle component 1

1

14

High-throughput

0.536

High

608681

CDKL2
Cyclin-dependent kinase-like 2

1

3

High-throughput

0.536

High

608688

CSN5
COP9 signalosome complex subunit 5

1

10

High-throughput

0.536

High

608690

CUL5
Cullin-5

1

16

High-throughput

0.536

High

608699

DCNL1
DCN1-like protein 1

1

1

High-throughput

0.536

High

608702

ZFR
Zinc finger RNA-binding protein

1

6

High-throughput

0.536

High

608706

RBM14
RNA-binding protein 14

1

9

High-throughput

0.536

High

608713

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

608719

SMAD5
Mothers against decapentaplegic homolog 5

1

10

Small-scale

0.536

High

608727

RBM42
RNA-binding protein 42

1

10

High-throughput

0.536

High

608756

SGK2
Serine/threonine-protein kinase Sgk2

1

5

High-throughput

0.536

High

608757

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

6

High-throughput

0.536

High

608771

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

15

High-throughput

0.536

High

608786

AGO2
Protein argonaute-2

1

8

High-throughput

0.536

High

608787

AGO1
Protein argonaute-1

1

8

High-throughput

0.536

High

608799

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.536

High

608633

RNF43
E3 ubiquitin-protein ligase RNF43

2

5

High-throughput

0.533

High

228962

AKAP8
A-kinase anchor protein 8

1

1

Small-scale

0.527

High

321960

NFAT5
Nuclear factor of activated T-cells 5

1

5

Small-scale

0.515

High

329892

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

1

High-throughput

0.515

High

557841

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.515

High

608808

STK24
Serine/threonine-protein kinase 24

1

8

High-throughput

0.515

High

608532

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.513

High

608604

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.513

High

211267

RFOX2
RNA binding protein fox-1 homolog 2

1

9

High-throughput

0.508

High

608466

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

10

High-throughput

0.508

High

608483

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.508

High

608517

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

13

High-throughput

0.508

High

608526

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

16

High-throughput

0.508

High

608557

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

9

High-throughput

0.508

High

608572

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

10

High-throughput

0.508

High

608732

RBM4
RNA-binding protein 4

1

11

High-throughput

0.508

High

608797

WBP11
WW domain-binding protein 11

1

2

High-throughput

0.508

High

608524

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

608537

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

608583

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

High-throughput

0.501

High

608689

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

10

High-throughput

0.501

High

352069

MBD3
Methyl-CpG-binding domain protein 3

1

0

Small-scale

0.493

High

608678

NDRG1
Protein NDRG1

1

0

Small-scale

0.493

High

568537

TNNT1
Troponin T, slow skeletal muscle

1

0

High-throughput

0.486

High

220222

FRS3
Fibroblast growth factor receptor substrate 3

1

1

High-throughput

0.481

High

125210

LEG9
Galectin-9

1

2

High-throughput

0.479

High

128761

MEN1
Menin

1

3

High-throughput

0.479

High

131316

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

7

Small-scale

0.479

High

134549

SAP18
Histone deacetylase complex subunit SAP18

1

4

High-throughput

0.479

High

135051

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

17

Small-scale

0.479

High

136823

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

5

High-throughput

0.479

High

137950

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

7

High-throughput

0.479

High

156933

CTRO
Citron Rho-interacting kinase

1

11

High-throughput

0.479

High

169936

AURKA
Aurora kinase A

1

8

High-throughput

0.479

High

172455

XPO1
Exportin-1

1

10

High-throughput

0.479

High

175832

SET1A
Histone-lysine N-methyltransferase SETD1A

1

8

Small-scale

0.479

High

187282

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

1

High-throughput

0.479

High

193981

R113A
E3 ubiquitin-protein ligase RNF113A

1

2

High-throughput

0.479

High

213798

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

4

High-throughput

0.479

High

222701

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

227360

SPOP
Speckle-type POZ protein

1

3

High-throughput

0.479

High

247658

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

251511

CCNT1
Cyclin-T1

1

3

High-throughput

0.479

High

257328

PAGE4
P antigen family member 4

1

2

High-throughput

0.479

High

258494

KIN17
DNA/RNA-binding protein KIN17

1

2

Small-scale

0.479

High

259406

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

271880

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

283428

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.479

High

293166

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

302689

SYUG
Gamma-synuclein

1

3

High-throughput

0.479

High

319375

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.479

High

324503

HEXI1
Protein HEXIM1

1

4

High-throughput

0.479

High

330646

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

335778

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

2

High-throughput

0.479

High

349782

SNAI1
Zinc finger protein SNAI1

1

3

High-throughput

0.479

High

351371

CBX7
Chromobox protein homolog 7

1

3

Small-scale

0.479

High

376699

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

1

High-throughput

0.479

High

377952

TNFA
Tumor necrosis factor

1

2

High-throughput

0.479

High

378826

CD4
T-cell surface glycoprotein CD4

1

1

Small-scale

0.479

High

385439

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

10

Small-scale

0.479

High

389000

FINC
Fibronectin

1

3

High-throughput

0.479

High

405771

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

411314

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.479

High

472441

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

High-throughput

0.479

High

482302

F16P1
Fructose-1,6-bisphosphatase 1

1

2

High-throughput

0.479

High

519722

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

534604

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

536455

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

540801

ERG
Transcriptional regulator ERG

1

4

Small-scale

0.479

High

550827

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

565132

ITA4
Integrin alpha-4

1

6

High-throughput

0.479

High

581619

MYOD1
Myoblast determination protein 1

1

1

Small-scale

0.479

High

583177

FOLR1
Folate receptor alpha

1

1

High-throughput

0.479

High

583814

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

1

6

Small-scale

0.479

High

586996

ITF2
Transcription factor 4

1

2

Small-scale

0.479

High

606183

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

608442

NUCL
Nucleolin

1

6

High-throughput

0.479

High

608446

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

608447

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

608450

CBL
E3 ubiquitin-protein ligase CBL

1

7

High-throughput

0.479

High

608451

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

8

Small-scale

0.479

High

608452

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

12

Small-scale

0.479

High

608453

TCEA1
Transcription elongation factor A protein 1

1

1

High-throughput

0.479

High

608454

GCSP
Glycine dehydrogenase

1

2

High-throughput

0.479

High

608456

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

608459

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.479

High

608462

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.479

High

608463

SHC1
SHC-transforming protein 1

1

8

High-throughput

0.479

High

608468

1433S
14-3-3 protein sigma

1

7

Small-scale

0.479

High

608471

MCM5
DNA replication licensing factor MCM5

1

6

High-throughput

0.479

High

608473

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

608476

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

High-throughput

0.479

High

608477

ZEB1
Zinc finger E-box-binding homeobox 1

1

3

Small-scale

0.479

High

608479

BRCA1
Breast cancer type 1 susceptibility protein

1

13

High-throughput

0.479

High

608481

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

608482

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

3

High-throughput

0.479

High

608486

MAGA3
Melanoma-associated antigen 3

1

6

Small-scale

0.479

High

608488

CRK
Adapter molecule crk

1

5

High-throughput

0.479

High

608489

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

10

High-throughput

0.479

High

608490

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

608491

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

3

High-throughput

0.479

High

608493

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.479

High

608494

SOX2
Transcription factor SOX-2

1

10

High-throughput

0.479

High

608495

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

608498

CTCF
Transcriptional repressor CTCF

1

2

Small-scale

0.479

High

608500

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

608502

GSK3A
Glycogen synthase kinase-3 alpha

1

8

High-throughput

0.479

High

608506

RORG
Nuclear receptor ROR-gamma

1

11

Small-scale

0.479

High

608508

MECP2
Methyl-CpG-binding protein 2

1

11

High-throughput

0.479

High

608509

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

7

High-throughput

0.479

High

608514

MK10
Mitogen-activated protein kinase 10

1

6

High-throughput

0.479

High

608515

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

5

High-throughput

0.479

High

608520

CD81
CD81 antigen

1

3

High-throughput

0.479

High

608525

WDR5
WD repeat-containing protein 5

1

9

High-throughput

0.479

High

608527

1433G
14-3-3 protein gamma

1

7

High-throughput

0.479

High

608529

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

608533

H4
Histone H4

1

4

High-throughput

0.479

High

608534

RBX1
E3 ubiquitin-protein ligase RBX1

1

1

High-throughput

0.479

High

608535

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

608539

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

608541

CNTP1
Contactin-associated protein 1

1

6

Small-scale

0.479

High

608545

H33
Histone H3.3

1

8

High-throughput

0.479

High

608547

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

608549

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.479

High

608551

RUNX1
Runt-related transcription factor 1

1

3

High-throughput

0.479

High

608553

EWS
RNA-binding protein EWS

1

12

High-throughput

0.479

High

608554

KIF23
Kinesin-like protein KIF23

1

6

High-throughput

0.479

High

608563

FOXO1
Forkhead box protein O1

1

6

High-throughput

0.479

High

608569

TRAF1
TNF receptor-associated factor 1

1

6

High-throughput

0.479

High

608570

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

7

High-throughput

0.479

High

608573

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

2

High-throughput

0.479

High

608574

RFA4
Replication protein A 30 kDa subunit

1

7

High-throughput

0.479

High

608579

IKZF1
DNA-binding protein Ikaros

1

3

High-throughput

0.479

High

608581

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

608582

SQSTM
Sequestosome-1

1

7

Small-scale

0.479

High

608595

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

5

High-throughput

0.479

High

608598

NBR1
Next to BRCA1 gene 1 protein

1

2

High-throughput

0.479

High

608602

MTF1
Metal regulatory transcription factor 1

1

3

High-throughput

0.479

High

608603

CUL7
Cullin-7

1

7

High-throughput

0.479

High

608606

TNIP1
TNFAIP3-interacting protein 1

1

13

High-throughput

0.479

High

608607

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

608608

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

608610

SF3A2
Splicing factor 3A subunit 2

1

4

High-throughput

0.479

High

608621

SMN
Survival motor neuron protein

1

1

Small-scale

0.479

High

608622

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

608625

MIDN
Midnolin

1

2

High-throughput

0.479

High

608631

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

9

High-throughput

0.479

High

608634

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

608635

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

2

High-throughput

0.479

High

608651

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

1

High-throughput

0.479

High

608652

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

608653

THOC4
THO complex subunit 4

1

4

Small-scale

0.479

High

608660

SMC5
Structural maintenance of chromosomes protein 5

1

5

High-throughput

0.479

High

608661

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

608662

SRRM1
Serine/arginine repetitive matrix protein 1

1

1

High-throughput

0.479

High

608664

RHG24
Rho GTPase-activating protein 24

1

4

High-throughput

0.479

High

608666

RYBP
RING1 and YY1-binding protein

1

3

Small-scale

0.479

High

608669

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

608670

TIP
T-cell immunomodulatory protein

1

2

High-throughput

0.479

High

608671

RBCC1
RB1-inducible coiled-coil protein 1

1

9

High-throughput

0.479

High

608672

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.479

High

608673

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.479

High

608676

TOPB1
DNA topoisomerase 2-binding protein 1

1

7

High-throughput

0.479

High

608677

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

608679

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

8

High-throughput

0.479

High

608682

REQU
Zinc finger protein ubi-d4

1

15

High-throughput

0.479

High

608683

CBP
CREB-binding protein

1

9

Small-scale

0.479

High

608684

KAT6A
Histone acetyltransferase KAT6A

1

13

High-throughput

0.479

High

608685

RBP56
TATA-binding protein-associated factor 2N

1

13

High-throughput

0.479

High

608687

CELF1
CUGBP Elav-like family member 1

1

8

High-throughput

0.479

High

608691

MED12
Mediator of RNA polymerase II transcription subunit 12

1

8

High-throughput

0.479

High

608693

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.479

High

608696

MBD6
Methyl-CpG-binding domain protein 6

1

8

High-throughput

0.479

High

608700

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.479

High

608701

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

7

Small-scale

0.479

High

608703

CI072
Guanine nucleotide exchange factor C9orf72

1

3

High-throughput

0.479

High

608707

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

2

High-throughput

0.479

High

608708

CIC
Protein capicua homolog

1

10

High-throughput

0.479

High

608711

CK5P2
CDK5 regulatory subunit-associated protein 2

1

8

Small-scale

0.479

High

608715

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

8

High-throughput

0.479

High

608718

NECD
Necdin

1

6

High-throughput

0.479

High

608721

ANM1
Protein arginine N-methyltransferase 1

1

5

High-throughput

0.479

High

608722

VRK1
Serine/threonine-protein kinase VRK1

1

4

High-throughput

0.479

High

608725

OVOL2
Transcription factor Ovo-like 2

1

2

Small-scale

0.479

High

608726

RIOK1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

608731

CP250
Centrosome-associated protein CEP250

1

6

High-throughput

0.479

High

608733

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.479

High

608734

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.479

High

608735

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

608736

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

12

High-throughput

0.479

High

608737

YTHD1
YTH domain-containing family protein 1

1

6

High-throughput

0.479

High

608738

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

6

High-throughput

0.479

High

608739

TRI31
E3 ubiquitin-protein ligase TRIM31

1

11

High-throughput

0.479

High

608740

IN80B
INO80 complex subunit B

1

2

High-throughput

0.479

High

608742

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

Small-scale

0.479

High

608745

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

608746

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

4

Small-scale

0.479

High

608747

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

608750

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.479

High

608753

ECT2
Protein ECT2

1

9

High-throughput

0.479

High

608758

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

7

High-throughput

0.479

High

608759

BRD7
Bromodomain-containing protein 7

1

12

High-throughput

0.479

High

608760

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

608763

MBNL1
Muscleblind-like protein 1

1

2

Small-scale

0.479

High

608764

FBX6
F-box only protein 6

1

3

High-throughput

0.479

High

608767

RNF12
E3 ubiquitin-protein ligase RLIM

1

2

High-throughput

0.479

High

608768

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

608773

MBD5
Methyl-CpG-binding domain protein 5

1

5

High-throughput

0.479

High

608774

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

5

High-throughput

0.479

High

608775

UBP35
Ubiquitin carboxyl-terminal hydrolase 35

1

10

Small-scale

0.479

High

608776

HDAC6
Protein deacetylase HDAC6

1

14

High-throughput

0.479

High

608780

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

608784

TF3C4
General transcription factor 3C polypeptide 4

1

1

Small-scale

0.479

High

608785

IKZF3
Zinc finger protein Aiolos

1

4

High-throughput

0.479

High

608789

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.479

High

608790

FAF1
FAS-associated factor 1

1

1

High-throughput

0.479

High

608791

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

4

High-throughput

0.479

High

608793

SRRM2
Serine/arginine repetitive matrix protein 2

1

7

High-throughput

0.479

High

608800

FBX7
F-box only protein 7

1

1

High-throughput

0.479

High

608801

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

12

Small-scale

0.479

High

608802

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

1

High-throughput

0.479

High

608803

YTHD2
YTH domain-containing family protein 2

1

6

High-throughput

0.479

High

608804

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

1

Small-scale

0.479

High

608806

RBM8A
RNA-binding protein 8A

1

14

High-throughput

0.479

High

608807

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

608809

SCC4
MAU2 chromatid cohesion factor homolog

1

1

High-throughput

0.479

High

352935

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.470

High

210240

PHF1
PHD finger protein 1

1

0

Small-scale

0.458

High

262014

NBN
Nibrin

1

0

Small-scale

0.458

High

277149

ZN217
Zinc finger protein 217

1

0

High-throughput

0.458

High

555333

SKI
Ski oncogene

1

0

Small-scale

0.458

High

568609

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.458

High

596845

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

608487

GATA4
Transcription factor GATA-4

1

0

High-throughput

0.458

High

608522

PSME3
Proteasome activator complex subunit 3

1

0

Small-scale

0.458

High

608531

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

608550

E2F1
Transcription factor E2F1

1

0

Small-scale

0.458

High

608623

VP26B
Vacuolar protein sorting-associated protein 26B

1

0

High-throughput

0.458

High

608644

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.458

High

608665

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

608668

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

608694

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

608697

OTUB1
Ubiquitin thioesterase OTUB1

1

0

Small-scale

0.458

High

608712

CRBN
Protein cereblon

1

0

Small-scale

0.458

High

608717

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

608720

CDC6
Cell division control protein 6 homolog

1

0

Small-scale

0.458

High

608728

DERL1
Derlin-1

1

0

Small-scale

0.458

High

608772

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.458

High

608796

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

608805

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.458

High

608519

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

4

Small-scale

0.457

High

608612

SF01
Splicing factor 1

1

9

High-throughput

0.457

High

608640

DUX4C
Double homeobox protein 4C

1

9

High-throughput

0.457

High

608765

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

608783

TNIK
TRAF2 and NCK-interacting protein kinase

1

4

High-throughput

0.457

High

322090

CDK14
Cyclin-dependent kinase 14

1

5

High-throughput

0.445

High

327789

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

15

High-throughput

0.445

High

354529

PAK4
Serine/threonine-protein kinase PAK 4

1

3

High-throughput

0.445

High

429265

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

442869

PRGR
Progesterone receptor

1

17

Small-scale

0.445

High

608501

CLK2
Dual specificity protein kinase CLK2

1

8

High-throughput

0.445

High

608504

TOB1
Protein Tob1

1

1

Small-scale

0.445

High

608512

NCBP2
Nuclear cap-binding protein subunit 2

1

16

High-throughput

0.445

High

608521

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

15

High-throughput

0.445

High

608523

FGF12
Fibroblast growth factor 12

1

2

Small-scale

0.445

High

608536

GRB2
Growth factor receptor-bound protein 2

1

5

High-throughput

0.445

High

608538

YBOX1
Y-box-binding protein 1

1

8

Small-scale

0.445

High

608556

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.445

High

608559

LG3BP
Galectin-3-binding protein

1

2

High-throughput

0.445

High

608568

STK4
Serine/threonine-protein kinase 4

1

8

High-throughput

0.445

High

608577

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

608585

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.445

High

608594

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

608600

CASP8
Caspase-8

1

2

High-throughput

0.445

High

608618

CRY1
Cryptochrome-1

1

5

Small-scale

0.445

High

608628

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.445

High

608629

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.445

High

608630

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

8

Small-scale

0.445

High

608636

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

608637

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

5

Small-scale

0.445

High

608642

NEK10
Serine/threonine-protein kinase Nek10

1

5

High-throughput

0.445

High

608704

CEP63
Centrosomal protein of 63 kDa

1

6

High-throughput

0.445

High

608716

ZBT18
Zinc finger and BTB domain-containing protein 18

1

5

High-throughput

0.445

High

608741

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

15

High-throughput

0.445

High

608743

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

15

High-throughput

0.445

High

608755

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.445

High

608794

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.445

High

105287

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

276056

NIPS2
Protein NipSnap homolog 2

1

2

Small-scale

0.437

High

318611

RHBT1
Rho-related BTB domain-containing protein 1

1

8

High-throughput

0.437

High

608645

KCTD9
BTB/POZ domain-containing protein KCTD9

1

4

High-throughput

0.437

High

608723

ZFY21
Zinc finger FYVE domain-containing protein 21

1

4

Small-scale

0.437

High

608730

RCAF1
GEL complex subunit OPTI

1

1

High-throughput

0.437

High

608769

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

2

High-throughput

0.437

High

608798

AAR2
Protein AAR2 homolog

1

3

High-throughput

0.437

High

467360

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.426

High

608484

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

608744

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

608751

ZN335
Zinc finger protein 335

1

0

Small-scale

0.426

High

608499

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

74751

B2Y833
TMPRSS2-ERG prostate cancer specific isoform 1

1

3

Small-scale

0.407

High

254787

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

608659

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.407

High

608754

GHC1
Mitochondrial glutamate carrier 1

1

4

High-throughput

0.407

High

608770

USE1
Vesicle transport protein USE1

1

1

Small-scale

0.407

High

377396

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

608639

FBX46
F-box only protein 46

1

0

Small-scale

0.249

Low

608650

SL9B2
Sodium/hydrogen exchanger 9B2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025