HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	26186194, 28514442, 33961781, 27114451, 16990800
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 908 Hs			1 407
+	Dm
		1179241 Q9VW54_DROME (3-906): 0: 1063: 60.65		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78
+	Sp
		953214 RPN1_SCHPO (8-905): 0: 1025: 47.67		RP13B_SCHPO (23-385): 4.4e-103: 312: 25.20
+	Hs
		1081035 PSMD1_HUMAN (59-845): 0: 790: 17.31		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Sp
		953221 RPN1_SCHPO (8-905): 0: 1025: 47.67		RP13A_SCHPO (244-387): 5.71e-28: 113: 27.78
+	Dm
		1179222 PSMD1_DROME (59-845): 0: 710: 17.07		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78
+	Ce
		998365 PSMD1_CAEEL (103-842): 0: 625: 16.77		ADRM1_CAEEL (15-407): 1.6e-107: 323: 32.69
+	Sp
		251854 RPN2_SCHPO (59-844): 0: 667: 16.61		RP13A_SCHPO (244-387): 5.71e-28: 113: 27.78