HitPredict

Interactor 1: PSMD2 (Q13200)
26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97) (Protein 55.11) (Tumor necrosis factor type 1 receptor-associated protein 2)
Gene: PSMD2

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 908 Hs			1 399
+	Hs
		1027733 PSMD2_HUMAN (1-908): 0: 1290: 100.00		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Hs
		1027821 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		1027815 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1027806 PSMD2_HUMAN (1-908): 0: 1290: 100.00		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		872151 PSMD2_HUMAN (1-908): 0: 1290: 100.00		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		923974 PSMD2_HUMAN (1-908): 0: 1290: 100.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Hs
		1136649 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Dm
		1374998 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		1259550 PSMD1_HUMAN (59-845): 0: 790: 17.31		DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75
+	Dm
		1362832 Q9VW54_DROME (3-906): 0: 1063: 60.65		Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88
+	Sc
		753827 RPN1_YEAST (49-906): 0: 869: 37.71		DDI1_YEAST (3-395): 7.99e-93: 287: 30.92
+	Sp
		953205 RPN1_SCHPO (8-905): 0: 1025: 47.67		DSK2_SCHPO (10-179): 8.15e-29: 117: 17.87
+	Sc
		753873 RPN1_YEAST (49-906): 0: 869: 37.71		DSK2_YEAST (19-213): 6.83e-31: 123: 15.49
+	Sc
		697080 RPN1_YEAST (49-906): 0: 869: 37.71		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Hs
		1303954 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		1303948 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1303937 PSMD1_HUMAN (59-845): 0: 790: 17.31		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		872202 PSMD1_HUMAN (59-845): 0: 790: 17.31		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Dm
		1359018 PSMD1_DROME (59-845): 0: 710: 17.07		Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39
+	Hs
		924124 PSMD1_HUMAN (59-845): 0: 790: 17.31		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06