Protein: LONM
Lon protease homolog, mitochondrial (EC 3.4.21.53)

Gene: LONM, PIM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 210
UniProt ID: P36775

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0004176 - ATP-dependent peptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

737148

LONM
Lon protease homolog, mitochondrial

3

17

Small-scale

0.834

High

705066

HSP78
Heat shock protein 78, mitochondrial

2

8

High-throughput

0.754

High

680628

HS104
Heat shock protein 104

2

9

High-throughput

0.737

High

543568

HSC82
ATP-dependent molecular chaperone HSC82

3

11

High-throughput

0.640

High

567962

MDHM
Malate dehydrogenase, mitochondrial

3

10

Small-scale

0.640

High

737172

PRS4
26S proteasome regulatory subunit 4 homolog

1

19

High-throughput

0.618

High

737210

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.618

High

737234

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.618

High

737182

MRX6
MIOREX complex component 6

3

0

Small-scale

0.613

High

737250

PET20
Protein PET20, mitochondrial

3

0

Small-scale

0.613

High

498496

METK1
S-adenosylmethionine synthase 1

2

1

High-throughput

0.588

High

657054

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

2

4

High-throughput

0.588

High

366139

HSP82
ATP-dependent molecular chaperone HSP82

2

11

High-throughput

0.584

High

737153

NCB5R
NADH-cytochrome b5 reductase 1

2

7

High-throughput

0.584

High

737174

MAM33
Mitochondrial acidic protein MAM33

2

3

High-throughput

0.584

High

367964

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.575

High

490938

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.571

High

737185

TOM22
Mitochondrial import receptor subunit TOM22

2

0

High-throughput

0.559

High

402933

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

7

Small-scale

0.553

High

493720

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

539338

KSS1
Mitogen-activated protein kinase KSS1

1

8

High-throughput

0.536

High

406978

RS3
Small ribosomal subunit protein uS3

2

4

High-throughput

0.533

High

549663

BGL2
Glucan 1,3-beta-glucosidase

2

1

High-throughput

0.533

High

737232

RS10A
Small ribosomal subunit protein eS10A

2

5

High-throughput

0.533

High

450420

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.513

High

399419

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.489

High

635503

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.489

High

737199

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

6

High-throughput

0.489

High

737208

USA1
U1 SNP1-associating protein 1

1

1

High-throughput

0.489

High

333314

CYC1
Cytochrome c isoform 1

1

1

High-throughput

0.479

High

334667

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

334922

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.479

High

341996

ATPB
ATP synthase subunit beta, mitochondrial

1

7

High-throughput

0.479

High

350804

RAS2
Ras-like protein 2

1

5

High-throughput

0.479

High

350869

YPT1
GTP-binding protein YPT1

1

4

High-throughput

0.479

High

388970

SYTC
Threonine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

404059

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

421758

KAD2
Adenylate kinase

1

1

High-throughput

0.479

High

423826

ATPA
ATP synthase subunit alpha, mitochondrial

1

7

High-throughput

0.479

High

430766

SYV
Valine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

450602

ATPO
ATP synthase subunit 5, mitochondrial

1

1

High-throughput

0.479

High

456741

HEM1
5-aminolevulinate synthase, mitochondrial

1

2

High-throughput

0.479

High

478114

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

482214

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.479

High

520515

RM02
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.479

High

558613

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

584152

ACON
Aconitate hydratase, mitochondrial

1

2

High-throughput

0.479

High

588038

HSP60
Heat shock protein 60, mitochondrial

1

6

High-throughput

0.479

High

593626

DBP4
ATP-dependent RNA helicase HCA4

1

4

High-throughput

0.479

High

614931

KC12
Casein kinase I homolog 2

1

2

High-throughput

0.479

High

626431

ERG6
Sterol 24-C-methyltransferase ERG6

1

2

High-throughput

0.479

High

633143

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.479

High

648365

NSR1
Nuclear localization sequence-binding protein

1

5

High-throughput

0.479

High

657228

URA7
CTP synthase 1

1

3

High-throughput

0.479

High

660905

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

5

High-throughput

0.479

High

677084

ATP7
ATP synthase subunit d, mitochondrial

1

2

Small-scale

0.479

High

686954

GLNA
Glutamine synthetase

1

5

High-throughput

0.479

High

688034

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

5

High-throughput

0.479

High

694513

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.479

High

737150

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.479

High

737151

MAK5
ATP-dependent RNA helicase MAK5

1

4

High-throughput

0.479

High

737154

KPR3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.479

High

737155

YHJ3
Uncharacterized protein YHR033W

1

1

High-throughput

0.479

High

737157

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

737158

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.479

High

737166

HXT6
High-affinity hexose transporter HXT6

1

4

High-throughput

0.479

High

737168

FHP
Flavohemoprotein

1

5

High-throughput

0.479

High

737171

NDH1
External NADH-ubiquinone oxidoreductase 1, mitochondrial

1

3

High-throughput

0.479

High

737176

PHB1
Prohibitin-1

1

5

Small-scale

0.479

High

737178

LSB3
LAS seventeen-binding protein 3

1

4

High-throughput

0.479

High

737179

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

737183

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.479

High

737186

PHB2
Prohibitin-2

1

5

Small-scale

0.479

High

737193

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.479

High

737200

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

2

High-throughput

0.479

High

737206

ESP1
Separin

1

1

High-throughput

0.479

High

737207

RT10
Small ribosomal subunit protein uS10m

1

4

High-throughput

0.479

High

737212

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

737213

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

737215

HFD1
Fatty aldehyde dehydrogenase HFD1

1

5

High-throughput

0.479

High

737218

RTN1
Reticulon-like protein 1

1

1

High-throughput

0.479

High

737219

DBP9
ATP-dependent RNA helicase DBP9

1

4

High-throughput

0.479

High

737231

HRK1
Serine/threonine-protein kinase HRK1

1

5

High-throughput

0.479

High

737237

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

8

High-throughput

0.479

High

737240

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

737243

RDL1
Thiosulfate:glutathione sulfurtransferase

1

1

High-throughput

0.479

High

737244

TCB1
Tricalbin-1

1

3

High-throughput

0.479

High

737249

ODC2
Mitochondrial 2-oxodicarboxylate carrier 2

1

4

High-throughput

0.479

High

336047

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.458

High

345240

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.458

High

357259

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

411233

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.458

High

527190

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.458

High

562218

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.458

High

601435

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.458

High

630794

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

699592

LIPA
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.458

High

732879

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

735321

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.458

High

735388

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.458

High

737149

CBP4
Assembly factor CBP4

1

0

High-throughput

0.458

High

737167

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

737169

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

737173

RT25
Small ribosomal subunit protein mS23

1

0

High-throughput

0.458

High

737181

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.458

High

737191

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

737196

ATPJ
ATP synthase subunit e, mitochondrial

1

0

High-throughput

0.458

High

737198

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.458

High

737202

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

737204

RPM2
Ribonuclease P protein component, mitochondrial

1

0

High-throughput

0.458

High

737209

RT08
Small ribosomal subunit protein uS8m

1

0

High-throughput

0.458

High

737217

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

737221

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.458

High

737223

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

737224

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

737225

PUF3
mRNA-binding protein PUF3

1

0

High-throughput

0.458

High

737235

NEW1
[NU+] prion formation protein 1

1

0

High-throughput

0.458

High

737238

ATPD
ATP synthase subunit delta, mitochondrial

1

0

High-throughput

0.458

High

737241

NCE2
Non-classical export protein 2

1

0

High-throughput

0.458

High

737248

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

424468

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.445

High

510974

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

555980

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

737162

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

141277

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

355454

H2B1
Histone H2B.1

1

5

High-throughput

0.437

High

355870

H2B2
Histone H2B.2

1

5

High-throughput

0.437

High

356416

H4
Histone H4

1

1

High-throughput

0.437

High

357486

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

358012

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

376747

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

High-throughput

0.437

High

405567

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

425014

DHE4
NADP-specific glutamate dehydrogenase 1

1

3

High-throughput

0.437

High

425117

LEUC
3-isopropylmalate dehydratase

1

2

High-throughput

0.437

High

425897

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

471001

RS22A
Small ribosomal subunit protein uS8A

1

4

High-throughput

0.437

High

498882

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.437

High

502982

SEC7
Protein transport protein SEC7

1

4

High-throughput

0.437

High

521186

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.437

High

526117

GAL2
Galactose transporter

1

4

High-throughput

0.437

High

542675

TAL1
Transaldolase

1

2

High-throughput

0.437

High

606619

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.437

High

631818

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.437

High

645386

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.437

High

661964

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

691527

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.437

High

693285

RPN2
26S proteasome regulatory subunit RPN2

1

16

High-throughput

0.437

High

693843

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.437

High

698771

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

7

High-throughput

0.437

High

700355

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

700845

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

701387

SC61A
Protein transport protein SEC61

1

3

High-throughput

0.437

High

703035

MRT4
Ribosome assembly factor MRT4

1

4

High-throughput

0.437

High

704322

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.437

High

729855

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.437

High

737152

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.437

High

737156

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

737164

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.437

High

737165

SEC31
Protein transport protein SEC31

1

10

High-throughput

0.437

High

737184

RL38
Large ribosomal subunit protein eL38

1

2

High-throughput

0.437

High

737187

YPT32
GTP-binding protein YPT32/YPT11

1

4

High-throughput

0.437

High

737188

ARO8
Aromatic/aminoadipate aminotransferase 1

1

1

High-throughput

0.437

High

737189

YGO0
Uncharacterized membrane protein YGL140C

1

1

High-throughput

0.437

High

737190

YG3A
Uncharacterized protein YGR130C

1

12

High-throughput

0.437

High

737192

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.437

High

737195

H3
Histone H3

1

6

High-throughput

0.437

High

737197

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.437

High

737201

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

737203

SMD1
Small nuclear ribonucleoprotein Sm D1

1

1

High-throughput

0.437

High

737211

HMO1
High mobility group protein 1

1

3

High-throughput

0.437

High

737214

UTP15
U3 small nucleolar RNA-associated protein 15

1

6

High-throughput

0.437

High

737227

RLP24
Ribosome biogenesis protein RLP24

1

2

High-throughput

0.437

High

737228

GAS5
1,3-beta-glucanosyltransferase GAS5

1

1

High-throughput

0.437

High

737229

NOP12
Nucleolar protein 12

1

4

High-throughput

0.437

High

737239

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.437

High

737245

CMR1
DNA damage-binding protein CMR1

1

7

High-throughput

0.437

High

737246

H2AZ
Histone H2A.Z

1

3

High-throughput

0.437

High

360842

TBB
Tubulin beta chain

1

4

High-throughput

0.407

High

737159

RPN1
26S proteasome regulatory subunit RPN1

1

16

High-throughput

0.407

High

737222

SUE1
Protein SUE1, mitochondrial

2

0

Small-scale

0.305

High

698649

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.279

Low

61575

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low

399743

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.249

Low

400173

CHO2
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.249

Low

540076

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.249

Low

593228

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.249

Low

605007

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

630716

AGP1
General amino acid permease AGP1

1

0

High-throughput

0.249

Low

657166

PYRD
Dihydroorotate dehydrogenase

1

0

High-throughput

0.249

Low

690019

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

High-throughput

0.249

Low

704976

ECT1
Ethanolamine-phosphate cytidylyltransferase

1

0

High-throughput

0.249

Low

733503

PET10
Protein PET10

1

0

High-throughput

0.249

Low

737160

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.249

Low

737161

GIC1
GTPase-interacting component 1

1

0

High-throughput

0.249

Low

737163

YHP7
Uncharacterized protein YHR097C

1

0

High-throughput

0.249

Low

737170

IES2
Ino eighty subunit 2

1

0

High-throughput

0.249

Low

737175

GVP36
Protein GVP36

1

0

High-throughput

0.249

Low

737180

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

737194

DOS2
Protein DOS2

1

0

High-throughput

0.249

Low

737205

MUK1
Protein MUK1

1

0

High-throughput

0.249

Low

737216

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

737220

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.249

Low

737226

NOC3
Nucleolar complex-associated protein 3

1

0

High-throughput

0.249

Low

737230

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.249

Low

737233

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.249

Low

737236

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.249

Low

737242

YORA4
Uncharacterized protein YOR114W

1

0

Small-scale

0.249

Low

737247

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.249

Low

737177

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024