Interactor 1: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8
Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31973889, 36688959, 21145461, 16949367, 26826127, 16751180, 29531219, 29225035, 34581821, 34526721, 37689310, 12732143, 22902626 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study, proximity labelling technology, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response GO:0031464 - Cul4A-RING E3 ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
