Protein: U1SBP
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (U11/U12 snRNP 35 kDa protein) (U11/U12-35K) (Protein HM-1) (U1 snRNP-binding protein homolog)

Gene: U1SBP, SNRNP35
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q16560

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005689 - U12-type spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1152327

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

3

6

High-throughput

0.861

High

1158757

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

2

20

High-throughput

0.811

High

1158759

RNPC3
RNA-binding region-containing protein 3

2

16

High-throughput

0.811

High

889742

CLK3
Dual specificity protein kinase CLK3

2

14

High-throughput

0.783

High

1028653

U2AF1
Splicing factor U2AF 35 kDa subunit

2

5

High-throughput

0.783

High

1006429

SRPK2
SRSF protein kinase 2

1

19

High-throughput

0.710

High

503702

SBK3
Uncharacterized serine/threonine-protein kinase SBK3

2

7

High-throughput

0.700

High

285941

SF3B1
Splicing factor 3B subunit 1

1

1

High-throughput

0.691

High

973931

RUXF
Small nuclear ribonucleoprotein F

3

11

High-throughput

0.675

High

605694

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.665

High

1158764

ZMAT5
Zinc finger matrin-type protein 5

1

0

High-throughput

0.656

High

973732

RUXE
Small nuclear ribonucleoprotein E

2

3

High-throughput

0.628

High

991189

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

8

High-throughput

0.628

High

472772

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

High-throughput

0.618

High

1158765

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.618

High

974138

RUXG
Small nuclear ribonucleoprotein G

2

18

High-throughput

0.611

High

1158752

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

2

0

High-throughput

0.602

High

1158756

PDCD7
Programmed cell death protein 7

2

0

High-throughput

0.602

High

1087658

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

3

High-throughput

0.587

High

956664

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

0

High-throughput

0.580

High

1158758

SNPC3
snRNA-activating protein complex subunit 3

2

0

High-throughput

0.580

High

344208

PTBP3
Polypyrimidine tract-binding protein 3

1

19

High-throughput

0.575

High

1158751

CCD57
Coiled-coil domain-containing protein 57

2

10

High-throughput

0.553

High

1158760

SYT17
Synaptotagmin-17

2

1

High-throughput

0.553

High

1158762

PKHF2
Pleckstrin homology domain-containing family F member 2

2

5

High-throughput

0.553

High

574290

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

8

High-throughput

0.536

High

974568

SMD2
Small nuclear ribonucleoprotein Sm D2

1

4

High-throughput

0.536

High

974755

SMD3
Small nuclear ribonucleoprotein Sm D3

1

12

High-throughput

0.536

High

1158753

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

5

High-throughput

0.536

High

1158755

PHF5A
PHD finger-like domain-containing protein 5A

1

1

High-throughput

0.536

High

631652

RAB6A
Ras-related protein Rab-6A

1

5

High-throughput

0.515

High

853275

CBX5
Chromobox protein homolog 5

1

3

High-throughput

0.515

High

934676

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.515

High

1158761

SNR25
U11/U12 small nuclear ribonucleoprotein 25 kDa protein

1

0

High-throughput

0.513

High

1104412

ILK
Scaffold protein ILK

1

5

High-throughput

0.508

High

1158754

ANR11
Ankyrin repeat domain-containing protein 11

1

6

High-throughput

0.481

High

824168

RL13A
Large ribosomal subunit protein uL13

1

5

High-throughput

0.479

High

821370

TCPZ
T-complex protein 1 subunit zeta

1

1

High-throughput

0.470

High

895567

SERPH
Serpin H1

1

4

High-throughput

0.470

High

1158763

GORS2
Golgi reassembly-stacking protein 2

1

4

High-throughput

0.470

High

1158766

X5D778
Ankyrin repeat domain 11 isoform A

1

7

High-throughput

0.470

High

164689

TNF11
Tumor necrosis factor ligand superfamily member 11

1

3

High-throughput

0.464

High

1153036

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

1

High-throughput

0.464

High

422181

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.457

High

71583

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

18

High-throughput

0.445

High

788932

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025