HitPredict

Interactor 1: DNJC3 (Q13217)
DnaJ homolog subfamily C member 3 (Endoplasmic reticulum DNA J domain-containing protein 6) (ER-resident protein ERdj6) (ERdj6) (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor of 58 kDa) (Protein kinase inhibitor p58)
Gene: DNAJC3

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TPR_1~TPR_2, TPR_16~TPR_2, TPR_19~TPR_2, TPR_2~TPR_8
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0016020 - membrane GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 412
+	Hs
		1053087 DNJB8_HUMAN (394-501): 4.62e-39: 143: 38.79		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		279297 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		1053045 DNJB7_HUMAN (394-501): 6.62e-35: 134: 38.94		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		636486 DNJB2_HUMAN (394-501): 1.3e-34: 134: 41.88		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		174884 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		684975 DNJC7_HUMAN (31-503): 8.06e-69: 230: 26.05		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		118655 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		118767 DNJB3_HUMAN (394-499): 9.96e-36: 131: 38.60		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		1012412 TMTC1_HUMAN (3-364): 7.42e-38: 150: 14.09		Q0VDC6_HUMAN (101-204): 3.56e-34: 125: 32.41
+	Hs
		118697 STIP1_HUMAN (24-460): 7.31e-16: 82: 10.91		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		684896 DNJB8_HUMAN (394-501): 4.62e-39: 143: 38.79		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		279279 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1034936 DNJB8_HUMAN (394-501): 4.62e-39: 143: 38.79		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		685058 DJB12_HUMAN (381-495): 7.69e-35: 136: 36.98		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		279295 DNJB5_HUMAN (392-495): 4.16e-36: 139: 39.13		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		636460 DNJB2_HUMAN (394-501): 1.3e-34: 134: 41.88		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Dm
		817472 Q9VPN5_DROME (18-164): 4.46e-22: 100: 17.69		FKB12_DROME (107-204): 8.02e-34: 123: 33.33
+	Hs
		174814 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		174661 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		174855 OGT1_HUMAN (13-134): 3.34e-16: 84: 18.03		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21