Protein: PYC2
Pyruvate carboxylase 2 (EC 6.4.1.1) (Pyruvic carboxylase 2) (PCB 2)

Gene: PYC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P32327

Gene Ontology (top 5):
GO:0004736 - pyruvate carboxylase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006090 - pyruvate metabolic process
GO:0006094 - gluconeogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

538329

PYC1
Pyruvate carboxylase 1

3

17

High-throughput

0.836

High

734305

SMC6
Structural maintenance of chromosomes protein 6

2

6

High-throughput

0.594

High

734284

PYC2
Pyruvate carboxylase 2

1

16

High-throughput

0.590

High

392393

HSP82
ATP-dependent molecular chaperone HSP82

2

9

High-throughput

0.571

High

544121

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.571

High

734292

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.552

High

656388

KC11
Casein kinase I homolog 1

1

7

High-throughput

0.536

High

557677

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.515

High

602362

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.500

High

675278

DMC1
Meiotic recombination protein DMC1

1

4

High-throughput

0.500

High

734295

RHO4
GTP-binding protein RHO4

1

2

High-throughput

0.500

High

459050

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

4

High-throughput

0.489

High

734296

SEN1
Helicase SEN1

1

0

Small-scale

0.486

High

368422

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

454715

KAPR
cAMP-dependent protein kinase regulatory subunit

1

4

Small-scale

0.479

High

579020

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

670445

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

726824

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

734286

RAD5
DNA repair protein RAD5

1

5

High-throughput

0.479

High

734287

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

734288

ATG8
Autophagy-related protein 8

1

8

High-throughput

0.479

High

734289

KPR2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.479

High

734294

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.479

High

734297

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.479

High

449086

CALM
Calmodulin

1

1

High-throughput

0.470

High

734293

MLC1
Myosin light chain 1

1

1

High-throughput

0.470

High

364973

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

439283

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

531271

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.458

High

645324

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

734302

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

576949

AMPL
Vacuolar aminopeptidase 1

1

1

High-throughput

0.457

High

523322

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

526143

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

734285

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

734291

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.445

High

558633

CAF20
Cap-associated protein CAF20

1

3

High-throughput

0.437

High

706458

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

734290

UME6
Transcriptional regulatory protein UME6

1

4

High-throughput

0.437

High

734298

YL352
F-box protein YLR352W

1

1

High-throughput

0.437

High

734299

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

734301

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

734303

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

734304

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

605102

TPM1
Tropomyosin-1

1

0

High-throughput

0.269

Low

734300

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025