HitPredict

Interactor 1: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Interactor 2: MAGI3 (Q5TCQ9)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)
Gene: MAGI3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.40	0.60	0.494

Property	Details
Experiments	10748157
Identification Methods	two hybrid array, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1484 Hs			1 1481
+	Hs
		1021485 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG1_HUMAN (14-594): 2.26e-26: 119: 9.03
+	Hs
		1028145 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG3_HUMAN (16-398): 1.65e-24: 113: 8.95
+	Rn
		962666 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG2_RAT (2-207): 4.15e-26: 118: 14.22
+	Mm
		963769 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG2_MOUSE (2-207): 6.64e-26: 117: 14.22
+	Mm
		963751 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG1_MOUSE (14-341): 2.85e-25: 115: 9.67
+	Hs
		1028139 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		SCRIB_HUMAN (16-566): 1.59e-18: 94.5: 16.00
+	Rn
		962664 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG3_RAT (16-398): 1.03e-23: 110: 8.70
+	Mm
		936175 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG3_MOUSE (16-398): 1.11e-23: 110: 8.70
+	Hs
		1028140 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG2_HUMAN (20-162): 2.63e-14: 80.4: 18.24
+	Hs
		942337 NMDE2_HUMAN (1-1484): 0: 1846: 100.00		DLG4_HUMAN (13-291): 3.17e-14: 80: 9.96
+	Rn
		962663 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG1_RAT (16-311): 1.59e-16: 87.8: 9.59
+	Rn
		677781 NMDE2_RAT (1-1484): 0: 1829: 98.45		DLG4_RAT (13-291): 2.72e-14: 80: 9.96
+	Mm
		963732 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		DLG4_MOUSE (19-236): 3.76e-14: 79.6: 12.05
+	Mm
		963735 NMDE2_MOUSE (1-1484): 0: 1826: 98.45		INADL_MOUSE (14-144): 7.47e-13: 75.9: 16.54
+	Rn
		291500 NMDE1_RAT (9-1484): 0: 1506: 52.59		MAGI2_RAT (308-1386): 4.83e-35: 148: 12.55
+	Mm
		723540 NMDE1_MOUSE (9-1484): 0: 1516: 52.79		GRIP1_MOUSE (16-699): 1.88e-15: 84.4: 11.40
+	Mm
		723533 NMDE1_MOUSE (9-1484): 0: 1516: 52.79		DLG4_MOUSE (19-236): 3.76e-14: 79.6: 12.05
+	Rn
		962655 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG1_RAT (16-311): 1.59e-16: 87.8: 9.59
+	Mm
		723534 NMDE1_MOUSE (9-1484): 0: 1516: 52.79		INADL_MOUSE (14-144): 7.47e-13: 75.9: 16.54
+	Rn
		677780 NMDE1_RAT (9-1484): 0: 1506: 52.59		DLG4_RAT (13-291): 2.72e-14: 80: 9.96