Interactor 1: GPS2 (Q13227)
G protein pathway suppressor 2 (GPS-2)
Gene: GPS2

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.937

The method score is based on:

Property Details
Experiments 21240272, 26186194, 28514442, 33961781, 24943844
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, molecular sieving, nuclear magnetic resonance, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains G_path_suppress~GPS2_interact
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0017053 - transcription repressor complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 327
Hs

1 2514
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024