Protein: AKAP5
A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein)

Gene: AKAP5
Organism: Homo sapiens
Interactions: 70
UniProt ID: P24588

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007193 - adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568549

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

6

4

Small-scale

0.737

High

623525

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

6

5

Small-scale

0.734

High

533787

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

6

5

Small-scale

0.731

High

610681

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

5

4

High-throughput

0.725

High

623537

PP2BA
Protein phosphatase 3 catalytic subunit alpha

4

1

Small-scale

0.696

High

349883

RASK
GTPase KRas

3

3

High-throughput

0.640

High

609644

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

4

High-throughput

0.628

High

498213

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

5

High-throughput

0.606

High

566288

KPCA
Protein kinase C alpha type

2

8

Small-scale

0.584

High

623531

RHOB
Rho-related GTP-binding protein RhoB

2

1

High-throughput

0.584

High

623547

TRPV1
Transient receptor potential cation channel subfamily V member 1

1

6

Small-scale

0.561

High

623553

ROP1L
Ropporin-1-like protein

2

1

High-throughput

0.553

High

623556

ROP1A
Ropporin-1A

2

1

High-throughput

0.553

High

623523

GBRB3
Gamma-aminobutyric acid receptor subunit beta-3

1

0

Small-scale

0.537

High

623526

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

Small-scale

0.537

High

623528

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

623551

TNPO1
Transportin-1

1

1

High-throughput

0.536

High

203626

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.513

High

414744

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.513

High

582069

NUCL
Nucleolin

1

0

High-throughput

0.513

High

623549

SMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2

1

0

High-throughput

0.513

High

623527

CLK1
Dual specificity protein kinase CLK1

1

1

High-throughput

0.489

High

623539

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

5

High-throughput

0.489

High

623550

IPO4
Importin-4

1

1

High-throughput

0.489

High

345333

FOS
Protein c-Fos

1

1

Small-scale

0.481

High

348517

RASN
GTPase NRas

1

3

High-throughput

0.479

High

503458

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

623529

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

623540

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

623543

TRPM8
Transient receptor potential cation channel subfamily M member 8

1

4

Small-scale

0.479

High

623548

TRPV3
Transient receptor potential cation channel subfamily V member 3

1

7

Small-scale

0.479

High

623557

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

6

Small-scale

0.479

High

623558

RXFP1
Relaxin receptor 1

1

1

Small-scale

0.479

High

623560

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

6

Small-scale

0.479

High

386115

P53
Cellular tumor antigen p53

1

0

Small-scale

0.460

High

623534

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.460

High

155278

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

178400

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

274703

TRPA1
Transient receptor potential cation channel subfamily A member 1

1

0

Small-scale

0.458

High

279439

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

417945

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

433582

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

506880

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

538838

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.458

High

544940

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

576985

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.458

High

623524

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

623530

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

623532

KCNJ2
Inward rectifier potassium channel 2

1

0

Small-scale

0.458

High

623535

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

623536

PRDX1
Peroxiredoxin-1

1

0

High-throughput

0.458

High

623541

OCLN
Occludin

1

0

High-throughput

0.458

High

623559

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

92659

E9PN89
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.445

High

623546

RM43
Large ribosomal subunit protein mL43

1

1

High-throughput

0.437

High

623555

DERL1
Derlin-1

1

1

High-throughput

0.437

High

623538

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

Small-scale

0.426

High

69761

B1AL05
Large ribosomal subunit protein mL43

1

1

High-throughput

0.407

High

73260

B4E1G1
Derlin

1

1

High-throughput

0.407

High

274493

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.279

Low

308169

LC7L3
Luc7-like protein 3

1

0

High-throughput

0.279

Low

623533

H31
Histone H3.1

1

0

High-throughput

0.279

Low

623542

RSBNL
Lysine-specific demethylase RSBN1L

1

0

High-throughput

0.279

Low

623545

OTU6B
Deubiquitinase OTUD6B

1

0

High-throughput

0.279

Low

623554

RMXL1
RNA binding motif protein, X-linked-like-1

1

0

High-throughput

0.279

Low

401437

JUN
Transcription factor Jun

1

0

Small-scale

0.251

Low

171196

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

305358

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

623544

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

623552

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024