HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35915203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016607 - nuclear speck
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 2610
+	Hs
		1028631 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1314644 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1031494 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		304138 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		992947 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		SMUF1_HUMAN (2220-2607): 1.5e-116: 391: 19.70
+	Hs
		125406 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125425 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125426 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		992925 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		1028813 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		304149 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		304010 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		516643 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		ITCH_HUMAN (2234-2608): 3.18e-117: 398: 21.88
+	Hs
		125430 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125122 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125374 SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		992771 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03
+	Hs
		952117 SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27
+	Hs
		1056624 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		TRIPC_HUMAN (5-1083): 4.48e-58: 225: 14.03