HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 496
+	Hs
		992868 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1028761 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		993788 SRSF4_HUMAN (5-265): 3.78e-51: 176: 53.64		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1028587 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1028844 SRSF5_HUMAN (1-240): 2.63e-54: 178: 100.00		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		1029029 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		903165 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		992990 SRSF1_HUMAN (2-170): 6.55e-57: 184: 43.68		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		1314629 RBM4_HUMAN (3-122): 5.32e-17: 81.7: 22.50		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		1028633 SRSF9_HUMAN (2-211): 1.47e-52: 172: 33.02		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		1029159 SRSF6_HUMAN (5-184): 1.35e-48: 165: 61.96		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		952150 SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		952072 SRSF3_HUMAN (4-78): 1.85e-11: 62.8: 47.56		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Mm
		1208017 RBM4_MOUSE (2-122): 2.58e-17: 82.4: 21.49		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		903196 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		516438 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1031495 PABP4_HUMAN (104-189): 3.45e-16: 80.1: 21.98		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Mm
		665772 PABP1_MOUSE (98-189): 1.29e-15: 78.2: 18.56		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		516740 PABP1_HUMAN (98-189): 1.16e-15: 78.6: 18.56		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68