Protein: WT1
Wilms tumor protein (WT33)

Gene: WT1
Organism: Homo sapiens
Interactions: 79
UniProt ID: P19544

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

575259

EGR1
Early growth response protein 1

2

18

Small-scale

0.768

High

585926

DVL3
Segment polarity protein dishevelled homolog DVL-3

3

14

High-throughput

0.671

High

585911

FL2D
Pre-mRNA-splicing regulator WTAP

4

0

Small-scale

0.670

High

585900

KR107
Keratin-associated protein 10-7

3

20

High-throughput

0.667

High

585918

HMBX1
Homeobox-containing protein 1

3

4

High-throughput

0.667

High

307281

RHIT
Transcriptional repressor RHIT

1

18

High-throughput

0.656

High

585919

TAOK1
Serine/threonine-protein kinase TAO1

1

6

High-throughput

0.656

High

585881

WT1
Wilms tumor protein

1

18

High-throughput

0.647

High

585913

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.647

High

585931

GLIS2
Zinc finger protein GLIS2

1

19

High-throughput

0.647

High

386073

P53
Cellular tumor antigen p53

3

6

Small-scale

0.646

High

150849

DVL2
Segment polarity protein dishevelled homolog DVL-2

2

10

High-throughput

0.640

High

585916

K1C40
Keratin, type I cytoskeletal 40

2

12

High-throughput

0.628

High

585896

KR103
Keratin-associated protein 10-3

2

20

High-throughput

0.613

High

178107

IPO8
Importin-8

2

20

High-throughput

0.606

High

585898

KR106
Keratin-associated protein 10-6

2

20

High-throughput

0.606

High

585932

OSBL3
Oxysterol-binding protein-related protein 3

2

1

High-throughput

0.606

High

585934

PICK1
PRKCA-binding protein

2

7

High-throughput

0.606

High

585936

ZRAN1
Ubiquitin thioesterase ZRANB1

2

10

High-throughput

0.606

High

146453

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.580

High

585917

TET2
Methylcytosine dioxygenase TET2

1

4

Small-scale

0.578

High

282817

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

13

Small-scale

0.573

High

585886

U2AF2
Splicing factor U2AF 65 kDa subunit

1

7

Small-scale

0.573

High

585903

UBC9
SUMO-conjugating enzyme UBC9

1

6

Small-scale

0.573

High

585928

PAWR
PRKC apoptosis WT1 regulator protein

1

1

Small-scale

0.573

High

585901

KR108
Keratin-associated protein 10-8

1

20

High-throughput

0.573

High

66979

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

134833

IMA3
Importin subunit alpha-3

1

9

High-throughput

0.541

High

168616

IMA6
Importin subunit alpha-6

1

9

High-throughput

0.541

High

320659

LDOC1
Protein LDOC1

1

3

High-throughput

0.541

High

528236

CCL5
C-C motif chemokine 5

1

1

High-throughput

0.541

High

585890

MAGA8
Melanoma-associated antigen 8

1

3

High-throughput

0.541

High

585895

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.541

High

585902

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.541

High

585905

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

High-throughput

0.541

High

585921

FAM9B
Protein FAM9B

1

2

High-throughput

0.541

High

585924

CEP70
Centrosomal protein of 70 kDa

1

5

High-throughput

0.541

High

585925

THRSP
Thyroid hormone-inducible hepatic protein

1

2

High-throughput

0.541

High

585930

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.541

High

585935

THAP1
THAP domain-containing protein 1

1

5

High-throughput

0.541

High

585937

ETV7
Transcription factor ETV7

1

19

High-throughput

0.541

High

506491

ARY2
Arylamine N-acetyltransferase 2

1

0

High-throughput

0.518

High

585904

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.518

High

585910

IDI1
Isopentenyl-diphosphate Delta-isomerase 1

1

0

High-throughput

0.518

High

585915

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.518

High

585920

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.518

High

349114

RASH
GTPase HRas

1

6

High-throughput

0.515

High

394093

A4
Amyloid-beta precursor protein

1

16

High-throughput

0.515

High

585884

DNJB1
DnaJ homolog subfamily B member 1

1

6

High-throughput

0.515

High

585889

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.515

High

585909

SQSTM
Sequestosome-1

1

5

High-throughput

0.515

High

271258

NPM3
Nucleoplasmin-3

1

4

High-throughput

0.508

High

174615

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

8

High-throughput

0.501

High

345899

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.501

High

585891

YAP1
Transcriptional coactivator YAP1

1

18

High-throughput

0.501

High

585906

SOX4
Transcription factor SOX-4

1

20

High-throughput

0.501

High

318060

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.494

High

585894

KLK7
Kallikrein-7

1

2

High-throughput

0.494

High

585907

GOGA2
Golgin subfamily A member 2

1

11

High-throughput

0.494

High

585929

CC136
Coiled-coil domain-containing protein 136

1

4

High-throughput

0.494

High

585887

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

585927

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

High-throughput

0.481

High

122490

MEN1
Menin

1

2

Small-scale

0.479

High

585882

TA2R
Thromboxane A2 receptor

1

2

Small-scale

0.479

High

585885

DNMT1
DNA

1

17

Small-scale

0.479

High

585888

HSP74
Heat shock 70 kDa protein 4

1

14

Small-scale

0.479

High

585892

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

585893

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.479

High

585914

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

Small-scale

0.479

High

585933

NANOG
Homeobox protein NANOG

1

8

High-throughput

0.479

High

585883

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.470

High

585912

SUZ12
Polycomb protein SUZ12

1

0

Small-scale

0.458

High

585897

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.457

High

585899

KR104
Keratin-associated protein 10-4

1

20

High-throughput

0.457

High

585908

GRIK2
Glutamate receptor ionotropic, kainate 2

1

1

High-throughput

0.417

High

585922

FMR1N
FMR1 neighbor protein

1

0

High-throughput

0.282

High

585923

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.282

High

557432

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024