HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 282
+	Hs
		992758 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		1028541 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		993707 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Dm
		580166 Q9V3W7_DROME (3-188): 2.19e-50: 170: 36.84		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Hs
		516478 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		1028644 SRSF5_HUMAN (2-180): 3.02e-46: 160: 64.25		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Dm
		580160 SRR55_DROME (3-337): 3.03e-47: 165: 46.86		TRA2_DROME (97-281): 1.36e-44: 153: 43.78
+	Zm
		30171 A0A1D6M1U3_MAIZE (4-206): 9.28e-61: 200: 36.15		A0A1D6K4S7_MAIZE (109-196): 6.8e-27: 110: 35.23
+	Hs
		516674 RBM4_HUMAN (1-343): 1.17e-47: 166: 17.05		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		516493 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		925011 SRSF1_HUMAN (3-188): 3.02e-54: 180: 36.65		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		925167 SRSF9_MOUSE (3-222): 3.56e-49: 166: 35.11		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Hs
		925020 SRSF9_HUMAN (3-222): 5.6e-49: 165: 34.22		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		925012 SRSF4_HUMAN (1-323): 1.85e-45: 163: 63.47		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		192621 SRSF5_MOUSE (2-180): 2.78e-46: 160: 64.25		TRA2B_MOUSE (1-279): 2.66e-34: 127: 52.30
+	Hs
		925021 SRSF6_HUMAN (1-323): 3.2e-43: 154: 100.00		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Mm
		857324 Q542V3_MOUSE (1-343): 1.15e-52: 182: 51.93		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Hs
		201707 RBM4B_HUMAN (1-343): 2.62e-45: 160: 18.23		MSI1H_HUMAN (100-255): 8.46e-26: 106: 22.22
+	Mm
		857340 SRSF1_MOUSE (3-188): 3.02e-54: 180: 36.65		TIA1_MOUSE (114-207): 2.24e-18: 86: 21.28
+	Mm
		936481 SRSF1_MOUSE (3-188): 3.02e-54: 180: 36.65		TIAR_MOUSE (113-253): 1.32e-16: 81: 18.52