Protein: UTRN
Utrophin (Dystrophin-related protein 1) (DRP-1)

Gene: UTRN
Organism: Homo sapiens
Interactions: 201
UniProt ID: P46939

Gene Ontology (top 5):
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0003779 - actin binding
GO:0005178 - integrin binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862736

DTNA
Dystrobrevin alpha

4

12

Small-scale

0.896

High

262372

DTNB
Dystrobrevin beta

3

14

Small-scale

0.847

High

547420

DMD
Dystrophin

2

15

High-throughput

0.811

High

862641

SNTB2
Beta-2-syntrophin

5

20

Small-scale

0.719

High

862669

MARK2
Serine/threonine-protein kinase MARK2

4

13

Small-scale

0.706

High

862647

DAG1
Dystroglycan 1

4

7

Small-scale

0.702

High

862661

TENS2
Tensin-2

4

17

High-throughput

0.697

High

862646

SNTB1
Beta-1-syntrophin

4

20

Small-scale

0.686

High

669162

ADA1D
Alpha-1D adrenergic receptor

4

5

Small-scale

0.683

High

862640

SNTA1
Alpha-1-syntrophin

3

20

Small-scale

0.676

High

862698

NDEL1
Nuclear distribution protein nudE-like 1

3

20

High-throughput

0.662

High

862664

CAVN1
Caveolae-associated protein 1

2

2

High-throughput

0.628

High

862678

RHPN1
Rhophilin-1

2

8

High-throughput

0.628

High

862713

CPNE5
Copine-5

2

5

High-throughput

0.628

High

862722

SNTG2
Gamma-2-syntrophin

2

20

High-throughput

0.628

High

224651

ACTN4
Alpha-actinin-4

1

17

High-throughput

0.618

High

439991

LCK
Tyrosine-protein kinase Lck

1

14

High-throughput

0.618

High

463397

LYN
Tyrosine-protein kinase Lyn

1

14

High-throughput

0.618

High

541390

FGFR1
Fibroblast growth factor receptor 1

1

17

High-throughput

0.618

High

648457

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

650082

FGFR3
Fibroblast growth factor receptor 3

1

17

High-throughput

0.618

High

710116

EPHA2
Ephrin type-A receptor 2

1

18

High-throughput

0.618

High

720156

UFO
Tyrosine-protein kinase receptor UFO

1

17

Small-scale

0.618

High

862618

TERF1
Telomeric repeat-binding factor 1

1

7

High-throughput

0.618

High

862631

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.618

High

862639

ANK3
Ankyrin-3

1

17

High-throughput

0.618

High

862642

SQSTM
Sequestosome-1

1

12

High-throughput

0.618

High

862653

TERF2
Telomeric repeat-binding factor 2

1

7

High-throughput

0.618

High

862668

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.618

High

862692

LRCH3
DISP complex protein LRCH3

1

7

High-throughput

0.618

High

862703

SAV1
Protein salvador homolog 1

1

3

High-throughput

0.618

High

862730

TES
Testin

1

11

High-throughput

0.618

High

862732

RCOR1
REST corepressor 1

1

3

High-throughput

0.618

High

862735

MYO6
Unconventional myosin-VI

1

13

High-throughput

0.618

High

862727

CTNL1
Alpha-catulin

2

12

Small-scale

0.612

High

692010

MARK3
MAP/microtubule affinity-regulating kinase 3

2

12

High-throughput

0.611

High

862710

PKHA2
Pleckstrin homology domain-containing family A member 2

2

7

Small-scale

0.611

High

862723

MARK1
Serine/threonine-protein kinase MARK1

2

13

High-throughput

0.611

High

862693

F167A
Protein FAM167A

3

3

High-throughput

0.604

High

822517

VHL
von Hippel-Lindau disease tumor suppressor

2

0

High-throughput

0.602

High

862694

LURA1
Leucine rich adaptor protein 1

2

1

High-throughput

0.601

High

862709

LIN7B
Protein lin-7 homolog B

2

20

High-throughput

0.601

High

862725

S53A1
Solute carrier family 53 member 1

2

2

High-throughput

0.601

High

862717

DISC1
Disrupted in schizophrenia 1 protein

2

7

High-throughput

0.590

High

337997

ABCA1
Phospholipid-transporting ATPase ABCA1

2

2

Small-scale

0.584

High

582705

EZRI
Ezrin

2

20

High-throughput

0.584

High

656068

PPIB
Peptidyl-prolyl cis-trans isomerase B

2

4

High-throughput

0.584

High

862626

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

862612

UTRN
Utrophin

1

14

Small-scale

0.575

High

395664

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

127020

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.546

High

862665

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

0

Small-scale

0.546

High

340098

PCNT
Pericentrin

1

20

High-throughput

0.541

High

143584

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

3

High-throughput

0.536

High

168651

CSKP
Peripheral plasma membrane protein CASK

1

19

High-throughput

0.536

High

539972

BCR
Breakpoint cluster region protein

1

20

High-throughput

0.536

High

540998

PIM1
Serine/threonine-protein kinase pim-1

1

13

High-throughput

0.536

High

566932

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.536

High

648764

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

8

High-throughput

0.536

High

682465

S100P
Protein S100-P

1

1

High-throughput

0.536

High

713154

NOS1
Nitric oxide synthase 1

1

4

High-throughput

0.536

High

755529

TTK
Dual specificity protein kinase TTK

1

9

High-throughput

0.536

High

853920

KI67
Proliferation marker protein Ki-67

1

11

High-throughput

0.536

High

862613

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

7

High-throughput

0.536

High

862637

DHX9
ATP-dependent RNA helicase A

1

4

High-throughput

0.536

High

862662

TENS3
Tensin-3

1

14

High-throughput

0.536

High

862674

TAGAP
T-cell activation Rho GTPase-activating protein

1

9

High-throughput

0.536

High

862676

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

4

High-throughput

0.536

High

862677

ARRD1
Arrestin domain-containing protein 1

1

11

High-throughput

0.536

High

862685

CPNE4
Copine-4

1

5

High-throughput

0.536

High

862687

ARRD3
Arrestin domain-containing protein 3

1

11

High-throughput

0.536

High

862691

AURKB
Aurora kinase B

1

4

High-throughput

0.536

High

862712

TENS1
Tensin-1

1

19

High-throughput

0.536

High

862720

SNTG1
Gamma-1-syntrophin

1

20

High-throughput

0.536

High

862728

FBLN5
Fibulin-5

1

6

High-throughput

0.536

High

862731

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

3

High-throughput

0.536

High

862733

KDIS
Kinase D-interacting substrate of 220 kDa

1

19

High-throughput

0.536

High

862737

RBM8A
RNA-binding protein 8A

1

3

High-throughput

0.536

High

161560

ITBP1
Integrin beta-1-binding protein 1

1

0

High-throughput

0.518

High

532440

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.515

High

862724

PI4KB
Phosphatidylinositol 4-kinase beta

1

6

High-throughput

0.515

High

63330

CFA69
Cilia- and flagella-associated protein 69

1

0

High-throughput

0.513

High

470268

NEP
Neprilysin

1

0

Small-scale

0.513

High

821252

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.513

High

862617

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.513

High

862632

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.513

High

862633

EREP3
Protein ENTREP3

1

0

High-throughput

0.513

High

862649

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.513

High

862657

PHF19
PHD finger protein 19

1

0

High-throughput

0.513

High

862673

MCLN2
Mucolipin-2

1

0

High-throughput

0.513

High

862675

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.513

High

862701

PDCL3
Phosducin-like protein 3

1

0

High-throughput

0.513

High

862707

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

862620

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

14

Small-scale

0.501

High

862629

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

Small-scale

0.500

High

862636

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

9

Small-scale

0.500

High

505807

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

4

High-throughput

0.494

High

426454

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.493

High

862656

INSY1
Inhibitory synaptic factor 1

1

3

High-throughput

0.489

High

862738

RPKL1
Ribosomal protein S6 kinase-like 1

1

8

High-throughput

0.489

High

862635

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

0

High-throughput

0.486

High

320386

SASH1
SAM and SH3 domain-containing protein 1

1

1

Small-scale

0.481

High

126497

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

193528

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

2

High-throughput

0.479

High

225953

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

246470

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.479

High

271972

OBSL1
Obscurin-like protein 1

1

18

High-throughput

0.479

High

299105

FLOT1
Flotillin-1

1

9

High-throughput

0.479

High

327190

ZFPL1
Zinc finger protein-like 1

1

4

High-throughput

0.479

High

330749

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

362016

AATM
Aspartate aminotransferase, mitochondrial

1

3

High-throughput

0.479

High

371428

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

375279

RASK
GTPase KRas

1

20

High-throughput

0.479

High

466144

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

536713

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

555943

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

580921

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

601207

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

603880

CXA1
Gap junction alpha-1 protein

1

8

High-throughput

0.479

High

715474

MARCS
Myristoylated alanine-rich C-kinase substrate

1

6

High-throughput

0.479

High

754755

H2B1B
Histone H2B type 1-B

1

6

High-throughput

0.479

High

764271

CTNA1
Catenin alpha-1

1

12

High-throughput

0.479

High

764531

CTNB1
Catenin beta-1

1

7

High-throughput

0.479

High

767399

RADI
Radixin

1

17

High-throughput

0.479

High

830311

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

845557

MUC18
Cell surface glycoprotein MUC18

1

9

High-throughput

0.479

High

862614

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.479

High

862615

GSK3A
Glycogen synthase kinase-3 alpha

1

17

High-throughput

0.479

High

862616

GSK3B
Glycogen synthase kinase-3 beta

1

18

High-throughput

0.479

High

862619

AFAD
Afadin

1

20

High-throughput

0.479

High

862621

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

862622

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

862623

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

862624

WDR5
WD repeat-containing protein 5

1

6

High-throughput

0.479

High

862625

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

862627

H4
Histone H4

1

4

High-throughput

0.479

High

862628

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

862630

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

862634

CAV1
Caveolin-1

1

12

High-throughput

0.479

High

862638

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

862643

HDAC1
Histone deacetylase 1

1

11

High-throughput

0.479

High

862644

CUL3
Cullin-3

1

9

High-throughput

0.479

High

862645

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.479

High

862651

PGM5
Phosphoglucomutase-like protein 5

1

3

Small-scale

0.479

High

862652

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.479

High

862654

OCLN
Occludin

1

6

High-throughput

0.479

High

862658

ARHGG
Rho guanine nucleotide exchange factor 16

1

11

High-throughput

0.479

High

862660

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

862663

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

862666

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

862667

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.479

High

862670

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

862672

CARM1
Histone-arginine methyltransferase CARM1

1

9

High-throughput

0.479

High

862679

PARD3
Partitioning defective 3 homolog

1

15

High-throughput

0.479

High

862680

HS105
Heat shock protein 105 kDa

1

7

High-throughput

0.479

High

862681

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

862683

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

Small-scale

0.479

High

862684

CK052
Uncharacterized protein C11orf52

1

5

High-throughput

0.479

High

862686

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

1

High-throughput

0.479

High

862688

PF21A
PHD finger protein 21A

1

8

High-throughput

0.479

High

862699

CCDC8
Coiled-coil domain-containing protein 8

1

8

High-throughput

0.479

High

862702

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

16

Small-scale

0.479

High

862704

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

862705

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

862706

RNF41
E3 ubiquitin-protein ligase NRDP1

1

12

Small-scale

0.479

High

862711

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

862714

E41LA
Band 4.1-like protein 4A

1

14

High-throughput

0.479

High

862715

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

High-throughput

0.479

High

862716

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

862718

LATS2
Serine/threonine-protein kinase LATS2

1

4

High-throughput

0.479

High

862719

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

862721

NDE1
Nuclear distribution protein nudE homolog 1

1

17

Small-scale

0.479

High

862729

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

862739

DUS10
Dual specificity protein phosphatase 10

1

3

High-throughput

0.479

High

353086

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.470

High

595991

H12
Histone H1.2

1

5

High-throughput

0.470

High

295301

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.458

High

446753

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

862697

IER2
Immediate early response gene 2 protein

1

0

High-throughput

0.458

High

862700

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

862659

OBI1
ORC ubiquitin ligase 1

1

1

High-throughput

0.457

High

62468

S35F4
Solute carrier family 35 member F4

1

5

High-throughput

0.445

High

190199

MOT4
Monocarboxylate transporter 4

1

4

High-throughput

0.445

High

600488

ZNF3
Zinc finger protein 3

1

1

High-throughput

0.445

High

628396

KLK2
Kallikrein-2

1

4

High-throughput

0.445

High

765232

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.445

High

862648

SCRIB
Protein scribble homolog

1

10

Small-scale

0.445

High

862655

CF184
Cilia- and flagella-associated protein 184

1

2

High-throughput

0.445

High

862690

CPNE2
Copine-2

1

5

High-throughput

0.445

High

862726

CPNE7
Copine-7

1

5

High-throughput

0.445

High

105534

APRIO
Alternative prion protein

1

9

High-throughput

0.437

High

862671

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

862682

ATOH1
Transcription factor ATOH1

1

8

Small-scale

0.437

High

862708

WDR76
WD repeat-containing protein 76

1

10

High-throughput

0.437

High

862734

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

Small-scale

0.437

High

503560

TFPT
TCF3 fusion partner

1

0

High-throughput

0.426

High

862696

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

862689

T3HPD
Trans-3-hydroxy-L-proline dehydratase

4

0

High-throughput

0.360

High

862650

PDK3
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

862695

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025