HitPredict

Interactor 1: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Interactor 2: Z354C (Q86Y25)
Zinc finger protein 354C (Kidney, ischemia, and developmentally-regulated protein 3) (hKID3)
Gene: ZNF354C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	32869873, 28514442, 33961781, 19850934, 31403225
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 835 Hs			1 554
+	Hs
		563268 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN708_HUMAN (10-553): 0: 722: 43.57
+	Hs
		977874 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF85_HUMAN (10-553): 0: 721: 46.40
+	Hs
		983756 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF91_HUMAN (69-553): 0: 618: 45.36
+	Hs
		970658 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF45_HUMAN (63-518): 0: 608: 45.40
+	Hs
		299537 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN432_HUMAN (90-551): 0: 595: 41.56
+	Hs
		64159 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN726_HUMAN (60-491): 0: 585: 43.81
+	Hs
		240840 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		Z354A_HUMAN (61-495): 8.7e-165: 483: 39.74
+	Hs
		200251 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN264_HUMAN (144-506): 1.5e-104: 328: 46.56
+	Hs
		73013 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		B4DU56_HUMAN (60-241): 9.05e-48: 177: 20.88
+	Hs
		846675 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF84_HUMAN (55-215): 2.2e-37: 149: 13.67
+	Hs
		728566 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF93_HUMAN (63-215): 1.61e-34: 139: 15.03
+	Hs
		67425 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN850_HUMAN (448-553): 1.06e-27: 120: 46.23
+	Hs
		264762 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN254_HUMAN (55-185): 6.87e-17: 85.8: 10.69
+	Hs
		997541 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN543_HUMAN (52-169): 1.04e-12: 72.7: 10.92
+	Hs
		977953 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF92_HUMAN (50-177): 3.65e-11: 67.7: 9.38
+	Hs
		549159 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN250_HUMAN (52-156): 1.6e-10: 65.8: 13.21
+	Hs
		258851 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		Z780A_HUMAN (58-158): 2.88e-10: 65: 9.90
+	Hs
		563251 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF12_HUMAN (55-156): 3.61e-10: 64.7: 10.78
+	Hs
		67864 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZN724_HUMAN (67-161): 1.89e-09: 62.3: 9.47
+	Hs
		563805 TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00		ZNF30_HUMAN (55-159): 7.46e-09: 60.4: 7.62