Interactor 1: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 22770219, 28514442, 31806563, 33306668, 33961781, 15014502, 21212736, 19270695, 33839758, 35440621, 19686743, 20663873, 23972993
Identification Methods affinity chromatography technology, pull down, enzymatic study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 424
Hs

1 496
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs

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Last updated: 15 Jul 2024