Protein: PGK
Phosphoglycerate kinase (EC 2.7.2.3)

Gene: PGK
Organism: Drosophila melanogaster
Interactions: 217
UniProt ID: Q01604

Gene Ontology (top 5):
GO:0004618 - phosphoglycerate kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis
GO:0006096 - glycolytic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578060

ENO
Enolase

2

3

High-throughput

0.571

High

1031185

Q7JX87
1-Cys peroxiredoxin

2

1

High-throughput

0.571

High

1031193

TERA
Transitional endoplasmic reticulum ATPase TER94

2

2

High-throughput

0.571

High

1031221

Q9V3V2
peptidylprolyl isomerase

2

3

High-throughput

0.571

High

1031232

Q9VAN7
Phosphoglycerate mutase

2

3

High-throughput

0.571

High

1031284

Q9VTY2
Uncharacterized protein, isoform A

2

4

High-throughput

0.571

High

1031293

Q9VVL7
Dihydrolipoyl dehydrogenase

2

2

High-throughput

0.571

High

460020

ALF
Fructose-bisphosphate aldolase

2

0

High-throughput

0.547

High

476926

NDKA
Nucleoside diphosphate kinase

2

0

High-throughput

0.547

High

855986

MOEH
Moesin/ezrin/radixin homolog 1

2

0

High-throughput

0.547

High

1031201

Q8IRD3
Glutathione peroxidase

2

0

High-throughput

0.547

High

1031240

Q9VEB1
Malate dehydrogenase, mitochondrial

2

0

High-throughput

0.547

High

649024

ANX10
Annexin B10

2

2

High-throughput

0.521

High

682726

PROF
Profilin

2

1

High-throughput

0.521

High

762529

UCHL
Ubiquitin carboxyl-terminal hydrolase

2

2

High-throughput

0.521

High

1031245

Q9VGK3
peptidylprolyl isomerase

2

3

High-throughput

0.521

High

1031262

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

2

1

High-throughput

0.521

High

1031273

Q9VPN5
Stress-induced-phosphoprotein 1

2

4

High-throughput

0.521

High

358477

ADH
Alcohol dehydrogenase

1

1

High-throughput

0.479

High

458092

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

4

High-throughput

0.479

High

1031303

Q9VYT3
FI23714p1

1

1

Small-scale

0.479

High

304510

AUB
Protein aubergine

1

0

Small-scale

0.458

High

567557

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.458

High

875407

KARG
Arginine kinase 1

1

0

High-throughput

0.458

High

1031289

PYRG
CTP synthase

1

0

High-throughput

0.458

High

1031320

PYG
Glycogen phosphorylase

1

0

High-throughput

0.458

High

47756

A0AQH0
Proteasome subunit beta

1

1

High-throughput

0.445

High

53992

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.445

High

121205

ALDR
Aldo-keto reductase 1B

1

4

High-throughput

0.445

High

197311

O18335
Rab11

1

1

High-throughput

0.445

High

234740

O46067
Hypoxia up-regulated protein 1

1

1

High-throughput

0.445

High

556657

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.445

High

611474

PSA4
Proteasome subunit alpha type-4

1

1

High-throughput

0.445

High

652734

PSA71
Proteasome subunit alpha type-7-1

1

1

High-throughput

0.445

High

726326

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

821827

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.445

High

822039

PSB1
Proteasome subunit beta type-1

1

3

High-throughput

0.445

High

835132

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

1

1

High-throughput

0.445

High

871609

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

3

High-throughput

0.445

High

1019578

TRXR1
Thioredoxin reductase 1, mitochondrial

1

1

High-throughput

0.445

High

1019845

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.445

High

1031171

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.445

High

1031178

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

3

High-throughput

0.445

High

1031184

Q7JVH6
LD24696p

1

4

High-throughput

0.445

High

1031187

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1031188

Q7K148
Proteasome subunit beta

1

1

High-throughput

0.445

High

1031190

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.445

High

1031192

Q7KKI0
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.445

High

1031200

Q8IQZ7
FI19014p1

1

2

High-throughput

0.445

High

1031217

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.445

High

1031224

THIO2
Thioredoxin-2

1

4

High-throughput

0.445

High

1031226

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.445

High

1031233

Q9VAY2
Heat shock protein 83

1

4

High-throughput

0.445

High

1031238

Q9VD02
GH14779p

1

1

High-throughput

0.445

High

1031241

FLNA
Filamin-A

1

2

High-throughput

0.445

High

1031242

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.445

High

1031247

Q9VH81
protein-serine/threonine phosphatase

1

1

High-throughput

0.445

High

1031249

Q9VHN7
transketolase

1

2

High-throughput

0.445

High

1031251

Q9VHX4
LD24679p

1

4

High-throughput

0.445

High

1031255

Q9VJJ0
Proteasome subunit beta

1

2

High-throughput

0.445

High

1031256

Q9VJZ6
LD40224p

1

6

High-throughput

0.445

High

1031261

EF1D
Probable elongation factor 1-delta

1

1

High-throughput

0.445

High

1031266

AK200
A-kinase anchor protein 200

1

2

High-throughput

0.445

High

1031267

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1031270

PSB4
Proteasome subunit beta type-4

1

6

High-throughput

0.445

High

1031277

Q9VQL1
serine--tRNA ligase

1

2

High-throughput

0.445

High

1031285

Q9VU35
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.445

High

1031287

Q9VUC1
Hsc70Cb, isoform A

1

2

High-throughput

0.445

High

1031301

CLIC
Chloride intracellular channel Clic

1

2

High-throughput

0.445

High

1031316

WUHO
tRNA

1

2

High-throughput

0.445

High

1031321

PSB3
Proteasome subunit beta type-3

1

3

High-throughput

0.445

High

1031325

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.445

High

1031327

Q9Y112
BcDNA.GH10614

1

4

High-throughput

0.445

High

1031198

Q8INH5
Aminopeptidase

1

1

High-throughput

0.437

High

1031207

Q8SWX4
Aminopeptidase

1

1

High-throughput

0.437

High

1031294

Q9VVM2
LP12049p

1

1

High-throughput

0.437

High

1031302

Q9VYR1
Regucalcin

1

1

High-throughput

0.437

High

52438

A1Z6X6
Lactoylglutathione lyase

1

0

High-throughput

0.426

High

357276

O97428
Ciboulot, isoform A

1

0

High-throughput

0.426

High

631724

JANA
Sex-regulated protein janus-A

1

0

High-throughput

0.426

High

632944

GLNA1
Glutamine synthetase 1, mitochondrial

1

0

High-throughput

0.426

High

874634

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.426

High

928948

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

1014685

CYC2
Cytochrome c-2

1

0

High-throughput

0.426

High

1031180

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.426

High

1031194

Q7KN85
ATP-citrate synthase

1

0

High-throughput

0.426

High

1031197

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.426

High

1031199

Q8INK3
Fatty acid-binding protein, muscle

1

0

High-throughput

0.426

High

1031203

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

1031206

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.426

High

1031208

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.426

High

1031209

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

1031215

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

1031227

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.426

High

1031230

Q9VAC1
GM14349p

1

0

High-throughput

0.426

High

1031237

Q9VCK6
LD34157p

1

0

High-throughput

0.426

High

1031243

Q9VG31
Malic enzyme

1

0

High-throughput

0.426

High

1031248

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

1031250

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.426

High

1031252

Q9VIE8
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.426

High

1031253

Q9VII9
Glyoxylate reductase/hydroxypyruvate reductase

1

0

High-throughput

0.426

High

1031258

Q9VKB0
threonine--tRNA ligase

1

0

High-throughput

0.426

High

1031259

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.426

High

1031260

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

0

High-throughput

0.426

High

1031265

Q9VLB7
Rab GDP dissociation inhibitor

1

0

High-throughput

0.426

High

1031269

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.426

High

1031274

Q9VPX6
Adenylyl cyclase-associated protein

1

0

High-throughput

0.426

High

1031280

Q9VRL1
GEO06356p1

1

0

High-throughput

0.426

High

1031282

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

1031288

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.426

High

1031295

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.426

High

1031300

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.426

High

1031309

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

1031312

Q9W3F6
Bleomycin hydrolase

1

0

High-throughput

0.426

High

1031323

4EBP
Eukaryotic translation initiation factor 4E-binding protein

1

0

High-throughput

0.426

High

57539

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.407

High

86473

B9EQV3
Endoplasmic reticulum transmembrane protein

1

1

High-throughput

0.407

High

145957

UGDH
UDP-glucose 6-dehydrogenase

1

1

High-throughput

0.407

High

356326

O97102
Small ubiquitin-related modifier

1

3

High-throughput

0.407

High

356539

O97121
cystathionine gamma-lyase

1

1

High-throughput

0.407

High

426653

HP1
Heterochromatin protein 1

1

2

High-throughput

0.407

High

561776

MODU
DNA-binding protein modulo

1

1

High-throughput

0.407

High

609377

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.407

High

648875

ANXB9
Annexin B9

1

2

High-throughput

0.407

High

657738

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

1

High-throughput

0.407

High

712336

CALR
Calreticulin

1

2

High-throughput

0.407

High

929470

PDI
Protein disulfide-isomerase

1

5

High-throughput

0.407

High

1031170

HMGD
High mobility group protein D

1

1

High-throughput

0.407

High

1031173

Q0E8X8
ATP synthase F1 subunit epsilon

1

1

High-throughput

0.407

High

1031179

NLP
Nucleoplasmin-like protein

1

1

High-throughput

0.407

High

1031181

Q3YMU0
Protein disulfide-isomerase

1

4

High-throughput

0.407

High

1031182

Q76NR6
Regucalcin

1

1

High-throughput

0.407

High

1031183

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.407

High

1031196

Q7KTJ7
Basigin, isoform G

1

2

High-throughput

0.407

High

1031204

Q8MYY7
RE44624p

1

4

High-throughput

0.407

High

1031225

PDIA6
Protein disulfide-isomerase A6 homolog

1

4

High-throughput

0.407

High

1031228

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.407

High

1031229

Q9V9U3
LD45254p

1

1

High-throughput

0.407

High

1031231

Q9VAC4
GEO09167p1

1

1

High-throughput

0.407

High

1031246

TCTP
Translationally-controlled tumor protein homolog

1

1

High-throughput

0.407

High

1031254

Q9VJD4
LD24721p

1

3

High-throughput

0.407

High

1031264

FKB59
FK506-binding protein 59

1

2

High-throughput

0.407

High

1031275

Q9VQ61
Aspartate aminotransferase

1

1

High-throughput

0.407

High

1031279

Q9VRD6
NTF2-related export protein

1

1

High-throughput

0.407

High

1031283

Q9VSL2
Glutathione S transferase O3

1

1

High-throughput

0.407

High

1031292

CHMP5
Charged multivesicular body protein 5

1

1

High-throughput

0.407

High

1031296

Q9VW70
FI21813p1

1

1

High-throughput

0.407

High

1031304

TXND5
Thioredoxin domain-containing protein 5 homolog

1

6

High-throughput

0.407

High

1031307

Q9W022
GEO01508p1

1

5

High-throughput

0.407

High

1031310

Q9W227
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.407

High

1031311

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

1

High-throughput

0.407

High

1031313

Q9W3X6
fumarate hydratase

1

1

High-throughput

0.407

High

1031315

CISY
Probable citrate synthase, mitochondrial

1

1

High-throughput

0.407

High

1031322

Q9XYZ9
Glutathione S transferase E12, isoform A

1

1

High-throughput

0.407

High

197749

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

2

0

High-throughput

0.298

High

1031218

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

0

High-throughput

0.298

High

1031278

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.282

High

393793

VIT2
Vitellogenin-2

1

0

High-throughput

0.249

Low

750530

FTZF1
Nuclear hormone receptor FTZ-F1

1

0

High-throughput

0.249

Low

1031176

LSP2
Larval serum protein 2

1

0

High-throughput

0.249

Low

1031202

Q8MSI2
GH15296p

1

0

High-throughput

0.249

Low

1031234

Q9VBA6
RE49565p

1

0

High-throughput

0.249

Low

1031257

Q9VK00
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

57761

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

195021

O16043
Anon1A4

1

0

High-throughput

0.232

Low

234552

VINC
Vinculin

1

0

High-throughput

0.232

Low

304612

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.232

Low

305184

TRMB
tRNA

1

0

High-throughput

0.232

Low

305645

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.232

Low

357487

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.232

Low

875155

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.232

Low

930120

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

1026623

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.232

Low

1031172

GRAP
Growth factor receptor-bound protein 2

1

0

High-throughput

0.232

Low

1031174

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

1031175

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.232

Low

1031177

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.232

Low

1031186

Q7JXC4
CG6459 protein

1

0

High-throughput

0.232

Low

1031189

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

1031191

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.232

Low

1031195

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.232

Low

1031205

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

1

0

High-throughput

0.232

Low

1031210

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

1031211

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.232

Low

1031212

VDAC
Voltage-dependent anion-selective channel

1

0

High-throughput

0.232

Low

1031213

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

1031214

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.232

Low

1031216

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

1031219

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.232

Low

1031220

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.232

Low

1031222

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.232

Low

1031223

Q9V3V9
Endonuclease G inhibitor, isoform A

1

0

High-throughput

0.232

Low

1031235

Q9VBR6
RE74917p

1

0

High-throughput

0.232

Low

1031236

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1031239

Q9VD29
small monomeric GTPase

1

0

High-throughput

0.232

Low

1031244

Q9VG33
Sulfurtransferase

1

0

High-throughput

0.232

Low

1031263

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

1031268

Q9VMU6
LD31822p

1

0

High-throughput

0.232

Low

1031271

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

1031272

Q9VP52
GH24315p

1

0

High-throughput

0.232

Low

1031276

BACC
Bacchus

1

0

High-throughput

0.232

Low

1031281

Q9VRP2
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1031286

WDR1
Actin-interacting protein 1

1

0

High-throughput

0.232

Low

1031290

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

1031291

Q9VVC5
2-oxoglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

1031297

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.232

Low

1031298

Q9VWQ7
Coactosin-like protein

1

0

High-throughput

0.232

Low

1031299

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.232

Low

1031305

Q9VZI1
Transgelin

1

0

High-throughput

0.232

Low

1031306

Q9VZY0
LD45195p

1

0

High-throughput

0.232

Low

1031308

Q9W0H8
Reticulocalbin-3

1

0

High-throughput

0.232

Low

1031314

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.232

Low

1031317

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.232

Low

1031318

Q9W478
RE43153p

1

0

High-throughput

0.232

Low

1031319

NSUN2
tRNA

1

0

High-throughput

0.232

Low

1031324

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.232

Low

1031326

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025