HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 523
+	Hs
		516495 PABP4_HUMAN (1-644): 0: 585: 100.00		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516608 PABP1_HUMAN (1-644): 0: 542: 74.54		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516339 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		516689 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP3_HUMAN (4-522): 2.67e-63: 219: 13.06
+	Hs
		516635 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		474021 PABP4_HUMAN (1-644): 0: 585: 100.00		PAB4L_HUMAN (147-425): 7.96e-26: 110: 13.89
+	Hs
		1119141 PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1020249 PABP4_HUMAN (1-644): 0: 585: 100.00		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		1031344 PABP4_HUMAN (1-644): 0: 585: 100.00		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		516484 PABP1_HUMAN (1-644): 0: 542: 74.54		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		516674 PABP1_HUMAN (1-644): 0: 542: 74.54		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Sc
		376562 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1055876 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		516355 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		474034 PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05		PABP5_HUMAN (86-416): 1.38e-52: 184: 16.90
+	Hs
		1020259 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65
+	Hs
		474019 PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05		ELAV2_HUMAN (84-156): 1.29e-13: 74.1: 31.65