HitPredict

Interactor 1: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 25624497, 28514442, 33961781, 35384245
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~fn3, fn3~ig, PK_Tyr_Ser-Thr~fn3, I-set~I-set, ig~I-set, I-set~LRR_8, Ig_3~I-set, Ig_3~ig, Ig_3~LRR_8, PK_Tyr_Ser-Thr~Y_phosphatase
Common GO terms GO:0005886 - plasma membrane
GO:0030424 - axon
GO:0043235 - receptor complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1948
Hs

1 839
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Last updated: 15 Jul 2024