HitPredict

Interactor 1: PTPRS (Q13332)
Receptor-type tyrosine-protein phosphatase S (R-PTP-S) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase sigma) (R-PTP-sigma)
Gene: PTPRS

Interactor 2: RN149 (Q8NC42)
E3 ubiquitin-protein ligase RNF149 (EC 2.3.2.27) (DNA polymerase-transactivated protein 2) (RING finger protein 149) (RING-type E3 ubiquitin transferase RNF149)
Gene: RNF149

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 36610398
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1948 Hs			1 400
+	Hs
		489989 PTPRF_HUMAN (1-1948): 0: 1528: 65.42		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		489996 PTPRF_HUMAN (1-1948): 0: 1528: 65.42		RN133_HUMAN (3-371): 1.3e-95: 292: 30.61
+	Hs
		489993 PTPRF_HUMAN (1-1948): 0: 1528: 65.42		RN128_HUMAN (11-387): 1.62e-91: 283: 38.38
+	Hs
		577043 PTPRA_HUMAN (1176-1948): 0: 815: 39.54		RN149_HUMAN (1-400): 4.22e-129: 378: 100.00
+	Hs
		577076 PTPRA_HUMAN (1176-1948): 0: 815: 39.54		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29
+	Hs
		617002 PTPRD_HUMAN (4-1463): 1.86e-106: 381: 16.51		RN133_HUMAN (3-371): 1.3e-95: 292: 30.61
+	Hs
		1262511 PTPRU_HUMAN (211-781): 3.44e-19: 97.4: 14.71		ZNRF4_HUMAN (32-389): 1.03e-53: 185: 18.35
+	Hs
		660879 PTPRM_HUMAN (33-462): 1.68e-09: 65.4: 12.86		AMFR_HUMAN (96-398): 5.47e-37: 143: 15.29