HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 336
+	Hs
		903455 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		RING2_HUMAN (1-336): 4.99e-112: 330: 100.00
+	Mm
		903677 WDR5_MOUSE (180-325): 1.26e-38: 141: 15.65		RING2_MOUSE (1-336): 4.78e-112: 330: 99.70
+	Hs
		717785 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		749452 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Hs
		1281338 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		RING2_HUMAN (1-336): 4.99e-112: 330: 100.00
+	Hs
		903159 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		196962 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		717626 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		903462 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		BARD1_HUMAN (1-291): 1.2e-38: 147: 12.42
+	Dm
		1279331 EBI_DROME (4-177): 1.25e-42: 157: 15.22		Q9VV77_DROME (36-334): 1.57e-34: 127: 16.50
+	Hs
		903492 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76
+	Hs
		749312 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Hs
		749764 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79
+	Hs
		718351 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		585027 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		RO52_HUMAN (36-286): 4.69e-43: 156: 13.55
+	Hs
		1305990 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		BARD1_HUMAN (1-291): 1.2e-38: 147: 12.42
+	Hs
		1019346 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		TRI26_HUMAN (36-282): 9.9e-36: 137: 17.90
+	Hs
		749983 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		BRCA1_HUMAN (36-214): 1.15e-33: 133: 25.79