HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 2752
+	Hs
		1288394 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		793042 LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		807711 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		1032101 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1032139 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		903450 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1164182 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		ZN469_HUMAN (653-2751): 4.46e-42: 173: 9.28
+	Hs
		1288258 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		MINT_HUMAN (709-2695): 5.55e-37: 157: 9.30
+	Hs
		903375 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		BD1L1_HUMAN (16-2752): 1.77e-19: 99.2: 9.13
+	Hs
		820867 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1264784 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Mm
		903669 WDR5_MOUSE (180-325): 1.26e-38: 141: 15.65		KMT2C_MOUSE (2097-2749): 1.31e-09: 66.6: 8.68
+	Hs
		903374 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		152622 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		152663 WDR5B_HUMAN (180-325): 2.45e-34: 129: 13.61		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75
+	Hs
		297832 BRWD3_HUMAN (65-317): 2.08e-26: 112: 15.72		K0754_HUMAN (864-1413): 2.27e-10: 69.1: 16.44
+	Hs
		1281391 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		PRR36_HUMAN (351-1530): 2.27e-26: 121: 9.95
+	Hs
		1281353 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		152678 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		KMT2D_HUMAN (10-501): 7.91e-09: 63.9: 11.75