HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 25228645, 17967884, 19242095, 31041561
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 2 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 440
Hs

1 485
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024