HitPredict

Interactor 1: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Interactor 2: JIP1 (Q9UQF2)
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)
Gene: MAPK8IP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.879

The method score is based on:

Property Details
Experiments 10490659, 28514442, 33961781
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PID~PID, SH3_9~SH3_9
Common GO terms GO:0005078 - MAP-kinase scaffold activity
GO:0005737 - cytoplasm
GO:0007254 - JNK cascade
GO:0008432 - JUN kinase binding
GO:0019894 - kinesin binding
and 2 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 824
Hs

1 711
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024