HitPredict

Interactor 1: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	28292929, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 154
+	Hs
		1079028 UB2V2_HUMAN (4-147): 8.54e-72: 213: 88.89		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		1377465 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		849494 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RNF11_HUMAN (1-154): 1.51e-42: 140: 100.00
+	Hs
		207572 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	Hs
		207545 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RNF13_HUMAN (77-146): 1.55e-26: 104: 33.80
+	At
		715137 UBC9_ARATH (12-146): 1.76e-57: 177: 23.70		RNG1L_ARATH (15-153): 5.68e-27: 104: 23.61
+	Hs
		1377467 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RN115_HUMAN (10-154): 2e-26: 102: 19.08
+	Hs
		1204871 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Zm
		74334 B4FC97_MAIZE (12-146): 2.27e-57: 177: 24.44		B6U926_MAIZE (52-153): 2.57e-25: 101: 29.52
+	Hs
		849359 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		GOLI_HUMAN (57-146): 1.98e-25: 101: 24.44
+	Hs
		849382 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RN128_HUMAN (57-153): 7.46e-25: 100: 25.77
+	Hs
		1356934 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	Hs
		849491 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RNF6_HUMAN (1-149): 3.51e-24: 99.2: 20.83
+	Hs
		849485 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RN150_HUMAN (57-146): 3.61e-24: 98.4: 26.67
+	At
		715139 UBC9_ARATH (12-146): 1.76e-57: 177: 23.70		RHG1A_ARATH (13-141): 1.35e-23: 97.6: 14.93
+	At
		715158 UBC11_ARATH (12-146): 1.93e-57: 177: 24.44		RHG1A_ARATH (13-141): 1.35e-23: 97.6: 14.93
+	Hs
		1346940 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		849459 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1332598 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77
+	Hs
		849446 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		RN167_HUMAN (77-143): 4.96e-21: 89.1: 36.77