Protein: GBP2
Serine/arginine (SR)-type shuttling mRNA binding protein GBP2 (Polyadenylate-binding protein GBP2) (RAP1 localization factor 6) (Single-strand telomeric DNA-binding protein GBP2) (G-strand-binding protein 2)

Gene: GBP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 132
UniProt ID: P25555

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000932 - P-body
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

676769

CTK1
CTD kinase subunit alpha

6

7

Small-scale

0.942

High

676781

YRA1
RNA annealing protein YRA1

6

18

Small-scale

0.940

High

676762

NOP3
Serine/arginine

5

19

Small-scale

0.909

High

676768

SKY1
Serine/threonine-protein kinase SKY1

2

20

Small-scale

0.812

High

656934

BUR1
Serine/threonine-protein kinase BUR1

2

8

High-throughput

0.802

High

517914

SSBP1
Single-stranded nucleic acid-binding protein

2

18

High-throughput

0.799

High

676726

HRB1
Serine/arginine

2

18

Small-scale

0.754

High

676779

NCBP2
Nuclear cap-binding protein subunit 2

2

18

High-throughput

0.754

High

605873

HPR1
THO complex subunit HPR1

8

2

Small-scale

0.750

High

676708

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

2

18

High-throughput

0.737

High

676754

THO2
THO complex subunit 2

6

5

Small-scale

0.732

High

676712

MFT1
THO complex subunit MFT1

5

2

Small-scale

0.712

High

676701

XPO1
Exportin-1

1

7

High-throughput

0.691

High

676704

KNS1
Dual specificity protein kinase KNS1

1

15

High-throughput

0.691

High

676746

CLA4
Serine/threonine-protein kinase CLA4

1

4

High-throughput

0.691

High

150152

THP2
THO complex subunit THP2

7

2

Small-scale

0.680

High

676730

IF4F1
Eukaryotic initiation factor 4F subunit p150

3

16

Small-scale

0.656

High

676758

TEX1
Protein TEX1

3

5

Small-scale

0.656

High

676748

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

2

2

High-throughput

0.628

High

403371

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

19

Small-scale

0.618

High

409957

RL25
Large ribosomal subunit protein uL23

1

5

High-throughput

0.618

High

434859

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.618

High

438388

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

6

High-throughput

0.618

High

676698

HRR25
Casein kinase I homolog HRR25

1

2

Small-scale

0.618

High

676714

NCBP1
Nuclear cap-binding protein complex subunit 1

1

6

Small-scale

0.618

High

676756

PAP2
Poly(A) RNA polymerase protein 2

1

2

Small-scale

0.618

High

676740

CTK2
CTD kinase subunit beta

2

2

Small-scale

0.611

High

453904

IF4E
Eukaryotic translation initiation factor 4E

2

5

Small-scale

0.611

High

676749

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

4

Small-scale

0.611

High

676775

SUB2
ATP-dependent RNA helicase SUB2

2

17

Small-scale

0.611

High

676700

RENT1
ATP-dependent helicase NAM7

2

16

Small-scale

0.584

High

676706

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

4

High-throughput

0.584

High

676780

RRP6
Exosome complex exonuclease RRP6

2

2

Small-scale

0.584

High

676784

MEX67
mRNA export factor MEX67

2

6

Small-scale

0.584

High

676755

NRD1
Protein NRD1

1

2

High-throughput

0.575

High

676761

NAM8
Protein NAM8

1

19

High-throughput

0.575

High

676785

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

20

High-throughput

0.575

High

454903

RS19A
Small ribosomal subunit protein eS19A

2

2

High-throughput

0.571

High

523181

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.552

High

543960

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

676732

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

676725

UTP9
U3 small nucleolar RNA-associated protein 9

1

1

High-throughput

0.536

High

676751

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.513

High

585213

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.489

High

676736

KRI1
Protein KRI1

1

2

High-throughput

0.489

High

676777

NOP6
Nucleolar protein 6

1

1

High-throughput

0.489

High

676741

CTK3
CTD kinase subunit gamma

1

0

Small-scale

0.480

High

149610

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

383538

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

433473

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

435798

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

441729

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

502873

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

504058

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.479

High

512020

RS4A
Small ribosomal subunit protein eS4A

1

2

High-throughput

0.479

High

512281

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

512843

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

514480

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

558601

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

594219

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

645302

XRN1
5'-3' exoribonuclease 1

1

7

Small-scale

0.479

High

674442

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

676694

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

676697

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

676699

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

676703

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

676710

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

676711

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

676713

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

676716

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

676717

EAP1
Protein EAP1

1

1

High-throughput

0.479

High

676718

GBLP
Small ribosomal subunit protein RACK1

1

7

High-throughput

0.479

High

676720

ATG8
Autophagy-related protein 8

1

13

High-throughput

0.479

High

676721

RS20
Small ribosomal subunit protein uS10

1

4

High-throughput

0.479

High

676724

NMD2
Nonsense-mediated mRNA decay protein 2

1

1

Small-scale

0.479

High

676727

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

676733

MLP2
Protein MLP2

1

10

High-throughput

0.479

High

676734

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

676735

PRP17
Pre-mRNA-processing factor 17

1

5

Small-scale

0.479

High

676739

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

676744

MTR4
ATP-dependent RNA helicase DOB1

1

13

Small-scale

0.479

High

676745

UPF3
Nonsense-mediated mRNA decay protein 3

1

1

Small-scale

0.479

High

676747

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

676750

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.479

High

676752

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

676757

GIS2
Zinc finger protein GIS2

1

9

High-throughput

0.479

High

676763

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

676764

RL6A
Large ribosomal subunit protein eL6A

1

3

High-throughput

0.479

High

676765

MLP1
Protein MLP1

1

10

Small-scale

0.479

High

676766

XRN2
5'-3' exoribonuclease 2

1

7

High-throughput

0.479

High

676767

TOM1
E3 ubiquitin-protein ligase TOM1

1

7

High-throughput

0.479

High

676770

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

676771

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

676772

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

676773

BRE1
E3 ubiquitin-protein ligase BRE1

1

6

Small-scale

0.479

High

676774

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

676778

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

676783

DCP1
mRNA-decapping enzyme subunit 1

1

2

Small-scale

0.479

High

577006

CBP7
Cytochrome B translational activator CBS2

1

0

High-throughput

0.458

High

672853

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

676715

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

676719

NU170
Nucleoporin NUP170

1

0

High-throughput

0.458

High

392306

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

394281

EF1A
Elongation factor 1-alpha

1

10

High-throughput

0.445

High

438257

NOT3
General negative regulator of transcription subunit 3

1

2

High-throughput

0.445

High

526031

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

584184

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

8

High-throughput

0.445

High

676695

FUN19
SWIRM domain-containing protein FUN19

1

1

High-throughput

0.445

High

676709

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

676722

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

676731

LSM4
LSM complex subunit LSM4

1

2

High-throughput

0.445

High

676742

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

6

High-throughput

0.445

High

676743

JJJ2
J protein JJJ2

1

2

High-throughput

0.445

High

676753

RBG2
Ribosome-interacting GTPase 2

1

3

High-throughput

0.445

High

676760

SEN1
Helicase SEN1

1

18

Small-scale

0.445

High

676776

LUC7
Protein LUC7

1

3

High-throughput

0.445

High

584890

TRM1
tRNA

1

0

High-throughput

0.438

High

676738

MOB2
CBK1 kinase activator protein MOB2

1

0

High-throughput

0.438

High

676693

KRR1
KRR1 small subunit processome component

1

4

High-throughput

0.437

High

676737

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

676782

DBP10
ATP-dependent RNA helicase DBP10

1

11

High-throughput

0.437

High

542946

CDC24
Cell division control protein 24

1

0

High-throughput

0.426

High

590549

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

676728

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.426

High

676729

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.426

High

456508

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

1

High-throughput

0.407

High

676696

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

1

High-throughput

0.407

High

676702

RM09
Large ribosomal subunit protein uL3m

1

2

High-throughput

0.407

High

676705

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

2

High-throughput

0.407

High

676707

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

1

High-throughput

0.407

High

676759

SFB2
SED5-binding protein 2

1

1

High-throughput

0.407

High

676723

SSF1
Ribosome biogenesis protein SSF1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025