HitPredict

Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Hs			1 768
+	Hs
		148070 DC1I1_HUMAN (1-638): 2.67e-129: 396: 75.04		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042655 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		903207 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042101 POC1B_HUMAN (199-446): 2.58e-28: 120: 9.62		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041672 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043513 DC2I2_HUMAN (190-623): 5.08e-84: 275: 19.75		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043085 WDR5B_HUMAN (367-626): 3.82e-61: 208: 16.15		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043441 WDR5B_HUMAN (367-626): 3.82e-61: 208: 16.15		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043562 TBL1R_HUMAN (317-624): 4.89e-57: 202: 13.11		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		245601 TBL1X_HUMAN (364-623): 2.38e-45: 171: 15.30		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		903208 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		792982 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		903209 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043114 POC1B_HUMAN (199-446): 2.58e-28: 120: 9.62		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043016 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043469 POC1B_HUMAN (199-446): 2.58e-28: 120: 9.62		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043376 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		903206 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Ce
		953926 LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50		CUL1_CAEEL (16-768): 0: 647: 26.01
+	Ce
		953927 LIN53_CAEEL (429-613): 2.09e-26: 114: 16.50		CUL2_CAEEL (30-768): 0: 613: 24.10