Interactor 1: ORC2 (Q13416)
Origin recognition complex subunit 2
Gene: ORC2

Interactor 2: ORC3 (Q9UBD5)
Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo)
Gene: ORC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 12614612, 31160578, 10402192, 15910003, 20850016, 26496610, 11395502, 17525332, 11323433, 37071682, 12004060, 16549788, 17716973
Identification Methods two hybrid, affinity chromatography technology, biochemical, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ORC2~ORC3_N, ORC2~ORC_WH_C
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0000808 - origin recognition complex
GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 577
Hs

1 711
+ Dm
+ At
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024