HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 626
+	Hs
		1033680 IKZF1_HUMAN (1-519): 0: 664: 100.00		POC1A_HUMAN (391-623): 1.51e-49: 179: 12.45
+	Hs
		1033684 IKZF1_HUMAN (1-519): 0: 664: 100.00		POC1B_HUMAN (435-626): 4.48e-37: 146: 12.95
+	Hs
		997708 IKZF1_HUMAN (1-519): 0: 664: 100.00		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		997953 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		1244152 ZN397_HUMAN (118-197): 2.27e-11: 68.2: 37.50		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Mm
		925840 ZN322_MOUSE (135-224): 1.27e-12: 71.6: 38.89		LIS1_MOUSE (118-478): 1.34e-50: 182: 9.73