HitPredict

Interactor 1: SNTA1 (Q13424)
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1)
Gene: SNTA1

Interactor 2: KS6A1 (Q15418)
Ribosomal protein S6 kinase alpha-1 (S6K-alpha-1) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (p90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPK-activated protein kinase 1a) (MAPKAP kinase 1a) (MAPKAPK-1a) (Ribosomal S6 kinase 1) (RSK-1)
Gene: RPS6KA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	1.00	0.527

Property	Details
Experiments	30726710
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 735
+	Hs
		1046432 SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		1033875 SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		850649 SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28		KS6A3_HUMAN (1-735): 0: 791: 79.14
+	Hs
		1073488 SNTG2_HUMAN (77-501): 8.81e-109: 335: 25.43		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		272861 SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28		KS6A4_HUMAN (49-734): 0: 649: 41.33
+	Hs
		1073489 ARHGC_HUMAN (41-468): 7.14e-46: 174: 17.87		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		850719 ARHGC_HUMAN (41-468): 7.14e-46: 174: 17.87		KS6A3_HUMAN (1-735): 0: 791: 79.14
+	Hs
		1073484 GOPC_HUMAN (55-169): 1.74e-29: 122: 41.38		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		942348 DLG4_HUMAN (44-364): 8.62e-24: 107: 16.91		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		1073453 LNX1_HUMAN (38-318): 2.23e-18: 90.4: 15.49		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		850715 GOPC_HUMAN (55-169): 1.74e-29: 122: 41.38		KS6A3_HUMAN (1-735): 0: 791: 79.14
+	Hs
		1073470 MAGI1_HUMAN (50-238): 1.06e-12: 72.9: 16.67		KS6A1_HUMAN (1-735): 0: 836: 100.00
+	Hs
		568658 SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62		KAPCA_HUMAN (414-712): 3.66e-114: 350: 29.71
+	Hs
		647889 SNTB1_HUMAN (8-505): 9.95e-157: 458: 47.62		MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48
+	Hs
		647885 SNTB2_HUMAN (3-504): 3.86e-150: 441: 45.28		MARK3_HUMAN (408-695): 1.9e-108: 348: 28.48
+	Hs
		272903 GOPC_HUMAN (55-169): 1.74e-29: 122: 41.38		KS6A4_HUMAN (49-734): 0: 649: 41.33
+	Mm
		933108 DLG4_MOUSE (44-364): 9.35e-24: 107: 16.91		KAPCB_MOUSE (416-712): 7.52e-113: 346: 29.90
+	Hs
		1071704 GOPC_HUMAN (55-169): 1.74e-29: 122: 41.38		KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80
+	Mm
		1143553 DLG4_MOUSE (44-364): 9.35e-24: 107: 16.91		KS6A2_MOUSE (2-331): 2.44e-102: 332: 23.68
+	Hs
		1021498 DLG1_HUMAN (1-320): 1.18e-24: 110: 15.34		KS6A2_HUMAN (2-321): 2.57e-98: 321: 23.80