Interactor 1: XRCC4 (Q13426)
DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]
Gene: XRCC4

Interactor 2: XRCC4 (Q13426)
DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]
Gene: XRCC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.930

The method score is based on:

Property Details
Experiments 25416956, 11080143, 25910212, 17567543, 16169070, 32296183, 21070942, 21768349, 31515488, unassigned1304
Identification Methods two hybrid, x-ray crystallography, affinity chromatography technology, two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid, molecular sieving, x ray scattering, light scattering, transmission electron microscopy and 2 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains XRCC4~XRCC4
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005958 - DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006302 - double-strand break repair
and 11 others

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Homologous interactions 0

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Last updated: 15 Jul 2024