Protein: SC6A5
Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)

Gene: SC6A5, SLC6A5
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q9Y345

Gene Ontology (top 5):
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0006836 - neurotransmitter transport
GO:0007268 - chemical synaptic transmission
GO:0015375 - glycine:sodium symporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

665752

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

3

2

High-throughput

0.662

High

1348366

GOGA5
Golgin subfamily A member 5

2

7

High-throughput

0.628

High

1357393

NAT14
Probable N-acetyltransferase 14

2

5

High-throughput

0.628

High

727548

SC6A6
Sodium- and chloride-dependent taurine transporter

1

9

High-throughput

0.575

High

1291530

RETR3
Reticulophagy regulator 3

2

4

High-throughput

0.574

High

1364101

SNX19
Sorting nexin-19

2

12

High-throughput

0.549

High

184532

SURF4
Surfeit locus protein 4

1

4

High-throughput

0.536

High

186449

TM9S1
Transmembrane 9 superfamily member 1

1

7

High-throughput

0.536

High

297290

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.536

High

344503

STR3N
STARD3 N-terminal-like protein

1

3

High-throughput

0.536

High

444028

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

2

High-throughput

0.536

High

467977

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

1

High-throughput

0.536

High

984342

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.536

High

1145186

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.536

High

1251764

CERS6
Ceramide synthase 6

1

13

High-throughput

0.536

High

1340123

ATLA2
Atlastin-2

1

1

High-throughput

0.536

High

1406249

CHP1
Calcineurin B homologous protein 1

1

4

High-throughput

0.536

High

1406737

SGMR1
Sigma non-opioid intracellular receptor 1

1

3

High-throughput

0.536

High

1428181

YIPF3
Protein YIPF3

1

5

High-throughput

0.536

High

1461267

AMFR
E3 ubiquitin-protein ligase AMFR

1

6

High-throughput

0.536

High

1461656

TBC24
TBC1 domain family member 24

1

1

High-throughput

0.536

High

506688

GPHRB
Golgi pH regulator B

2

7

High-throughput

0.533

High

992462

GBG5

1

0

High-throughput

0.513

High

1428321

DERL2
Derlin-2

1

0

High-throughput

0.513

High

1429441

T126A
Transmembrane protein 126A

1

0

High-throughput

0.513

High

85416

GPHRA
Golgi pH regulator A

2

7

High-throughput

0.504

High

165677

SCAM3
Secretory carrier-associated membrane protein 3

1

3

High-throughput

0.489

High

1141569

OXA1L
Mitochondrial inner membrane protein OXA1L

1

1

High-throughput

0.489

High

1203401

YIF1B
Protein YIF1B

1

2

High-throughput

0.489

High

1322223

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

3

High-throughput

0.489

High

1347675

NPL4
Nuclear protein localization protein 4 homolog

1

1

High-throughput

0.489

High

1370003

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

1

High-throughput

0.489

High

1380500

YIPF5
Protein YIPF5

1

3

High-throughput

0.489

High

1384198

TM186
Transmembrane protein 186

1

2

High-throughput

0.489

High

467664

4F2
Amino acid transporter heavy chain SLC3A2

1

2

Small-scale

0.479

High

1159662

STX1A
Syntaxin-1A

1

15

Small-scale

0.479

High

522758

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

6

High-throughput

0.445

High

716646

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

4

High-throughput

0.445

High

761546

HS71L
Heat shock 70 kDa protein 1-like

1

3

High-throughput

0.445

High

1408214

RNF5
E3 ubiquitin-protein ligase RNF5

1

3

High-throughput

0.445

High

1445755

WDR6
tRNA

1

2

High-throughput

0.445

High

1348589

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.439

High

732433

PRDX2
Peroxiredoxin-2

1

4

High-throughput

0.407

High

944356

TMM33
Transmembrane protein 33

1

1

High-throughput

0.407

High

1097083

PRDX4
Peroxiredoxin-4

1

4

High-throughput

0.407

High

1333725

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.279

Low

1361378

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

347433

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.232

Low

716754

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.232

Low

1459031

TRM7
tRNA

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025