HitPredict

Interactor 1: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Interactor 2: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24711643
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1488 Hs			1 1698
+	Hs
		1056833 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		807727 MAP1B_HUMAN (41-1111): 4.34e-44: 178: 10.34		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		944679 MAP1A_HUMAN (34-656): 9.21e-10: 66.1: 10.05		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		1061523 TITIN_HUMAN (91-778): 3.15e-09: 64.2: 9.45		CUL7_HUMAN (1-1698): 0: 2861: 100.00
+	Hs
		1057026 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		APC10_HUMAN (830-969): 1.42e-51: 181: 23.45
+	Hs
		319840 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55
+	Hs
		152570 KMT2D_HUMAN (751-1487): 2.54e-13: 77.6: 8.66		HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55
+	Dm
		1370265 Q9VLS7_DROME (156-1116): 1.76e-16: 87.9: 12.00		HERC2_DROME (356-456): 1.04e-33: 145: 32.69