HitPredict

Interactor 1: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Interactor 2: TENS4 (Q8IZW8)
Tensin-4 (C-terminal tensin-like protein)
Gene: TNS4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 694 Hs			1 715
+	Hs
		1035381 GAB1_HUMAN (1-694): 0: 547: 100.00		TENS3_HUMAN (1-714): 7.94e-77: 271: 26.80
+	Hs
		1035409 GAB1_HUMAN (1-694): 0: 547: 100.00		TENS1_HUMAN (9-712): 2.82e-68: 246: 29.79
+	Mm
		403466 GAB1_MOUSE (1-694): 0: 544: 89.93		SRC_MOUSE (287-582): 2.58e-22: 103: 14.89
+	Hs
		522965 GAB1_HUMAN (1-694): 0: 547: 100.00		SRC_HUMAN (287-582): 1.42e-21: 100: 14.56
+	Hs
		1035406 GAB1_HUMAN (1-694): 0: 547: 100.00		SLAP2_HUMAN (399-601): 2.94e-21: 95.9: 22.22
+	Hs
		1028466 GAB1_HUMAN (1-694): 0: 547: 100.00		SLAP1_HUMAN (382-578): 2.29e-16: 82: 17.70
+	Hs
		523213 GAB2_HUMAN (3-691): 2.24e-153: 461: 39.01		SRC_HUMAN (287-582): 1.42e-21: 100: 14.56
+	Hs
		523086 GAB3_HUMAN (1-683): 1.81e-103: 329: 28.82		SRC_HUMAN (287-582): 1.42e-21: 100: 14.56
+	Hs
		203234 PKHA7_HUMAN (5-485): 5.86e-74: 260: 12.07		SYNJ1_HUMAN (271-615): 7.07e-18: 90.6: 12.40
+	Hs
		867129 PKHA2_HUMAN (2-210): 3.77e-36: 143: 19.28		SC24C_HUMAN (202-494): 4.53e-10: 65.1: 12.09
+	Dm
		113976 M9PB30_DROME (113-693): 9.4e-14: 77.5: 13.46		M9PB30_DROME (8-625): 2.4e-09: 63.2: 8.15