HitPredict

Interactor 1: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Interactor 2: LHX4 (Q969G2)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II and 2 others more... GO:0043565 - sequence-specific DNA binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	552
Hs

1	390

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024