Interactor 1: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Interactor 2: SFRP2 (Q96HF1)
Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1)
Gene: SFRP2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 24412244
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0008285 - negative regulation of cell population proliferation
GO:0030308 - negative regulation of cell growth
GO:0030509 - BMP signaling pathway
GO:0042733 - embryonic digit morphogenesis
GO:0045892 - negative regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 552
Hs

1 295
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024