Interactor 1: VPP3 (Q13488)
V-type proton ATPase 116 kDa subunit a 3 (V-ATPase 116 kDa subunit a 3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3)
Gene: TCIRG1

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains V_ATPase_I~V_ATPase_I
Common GO terms GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
and 6 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 830
Hs

1 856
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc

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Last updated: 15 Jul 2024