HitPredict

Interactor 1: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30948266, 23524849
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 2554
+	Hs
		1036311 BIRC2_HUMAN (2-604): 0: 643: 72.31		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		177706 BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		1035953 BIRC3_HUMAN (1-604): 0: 676: 100.00		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		1036312 BIRC2_HUMAN (2-604): 0: 643: 72.31		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		957762 XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21		UBP47_HUMAN (1465-2053): 7.75e-108: 381: 19.49
+	Hs
		957751 XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		1264871 RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		177733 BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00		UBP22_HUMAN (1505-1931): 1.76e-100: 336: 17.68