Protein: QPCTL
Glutaminyl-peptide cyclotransferase-like protein (EC 2.3.2.5) (Golgi-resident glutaminyl-peptide cyclotransferase) (isoQC) (gQC)

Gene: QPCTL
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9NXS2

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005794 - Golgi apparatus
GO:0008270 - zinc ion binding
GO:0016020 - membrane
GO:0016603 - glutaminyl-peptide cyclotransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

828460

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.638

High

1306973

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

3

1

High-throughput

0.609

High

397076

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1437069

AGO3
Protein argonaute-3

1

1

High-throughput

0.536

High

1452102

FA13B
Protein FAM13B

2

1

High-throughput

0.521

High

1452107

RHG26
Rho GTPase-activating protein 26

2

2

High-throughput

0.521

High

889020

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.513

High

439861

INSR
Insulin receptor

1

1

High-throughput

0.500

High

972058

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.493

High

1120042

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

1

High-throughput

0.489

High

423319

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

157921

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

243125

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

331367

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

350152

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

401592

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

914024

CHIO
Beta-chimaerin

1

1

High-throughput

0.479

High

939979

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.479

High

1114458

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1215862

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1367427

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1438046

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

1452103

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

158336

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.458

High

218855

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

302648

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

316078

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

320096

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

1005171

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1034074

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.458

High

1140942

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1280555

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1312617

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1404801

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

1452104

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

1452109

RNF11
RING finger protein 11

1

0

Small-scale

0.458

High

951876

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.457

High

1157089

NTRK3
NT-3 growth factor receptor

1

1

High-throughput

0.457

High

1139591

S39AE
Metal cation symporter ZIP14

1

5

High-throughput

0.445

High

1242960

S39A4
Zinc transporter ZIP4

1

5

High-throughput

0.445

High

1251194

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.445

High

1337985

ZNT7
Zinc transporter 7

1

3

High-throughput

0.445

High

1346806

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

3

High-throughput

0.445

High

1363465

S39A7
Zinc transporter SLC39A7

1

5

High-throughput

0.445

High

1439202

AGO4
Protein argonaute-4

1

1

High-throughput

0.445

High

1452111

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

3

High-throughput

0.445

High

65917

RHG42
Rho GTPase-activating protein 42

1

2

High-throughput

0.437

High

349263

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.437

High

472358

CFAH
Complement factor H

1

1

Small-scale

0.437

High

626379

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.437

High

891829

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.437

High

971188

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1035952

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

1218392

ARHGG
Rho guanine nucleotide exchange factor 16

1

1

High-throughput

0.437

High

1369947

ARHG1
Rho guanine nucleotide exchange factor 1

1

1

High-throughput

0.437

High

1397493

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

1438963

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

1

High-throughput

0.437

High

1452106

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.437

High

722645

CTR1
High affinity cationic amino acid transporter 1

1

0

High-throughput

0.426

High

948946

CD81
CD81 antigen

1

0

High-throughput

0.426

High

1058324

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.426

High

1209729

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1326118

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1105250

S39A6
Zinc transporter ZIP6

1

5

High-throughput

0.407

High

1251813

S39A5
Zinc transporter ZIP5

1

5

High-throughput

0.407

High

1421367

S39A8
Metal cation symporter ZIP8

1

5

High-throughput

0.407

High

1203816

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.316

High

1249449

OLFM4
Olfactomedin-4

2

0

High-throughput

0.316

High

1447345

ANLN
Anillin

2

0

High-throughput

0.305

High

1163877

DUS6
Dual specificity protein phosphatase 6

2

0

High-throughput

0.298

High

1391060

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.298

High

66904

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

373315

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.279

Low

549353

SRF
Serum response factor

1

0

High-throughput

0.279

Low

964755

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.279

Low

1270659

COX15
Heme A synthase COX15

1

0

High-throughput

0.279

Low

1428653

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.269

Low

124655

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.249

Low

223377

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

257509

PAGE4
P antigen family member 4

1

0

High-throughput

0.249

Low

294428

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

482547

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.249

Low

582632

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.249

Low

766226

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.249

Low

831535

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

842998

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

0

High-throughput

0.249

Low

897408

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.249

Low

1024885

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1026563

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low

1096247

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.249

Low

1116314

PTC1
Protein patched homolog 1

1

0

Small-scale

0.249

Low

1249265

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1306927

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.249

Low

1327234

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1338402

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1350215

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

0

High-throughput

0.249

Low

1386473

KLH29
Kelch-like protein 29

1

0

High-throughput

0.249

Low

1391807

AURKB
Aurora kinase B

1

0

High-throughput

0.249

Low

1393764

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1448283

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

1452105

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.249

Low

1452108

FAF1
FAS-associated factor 1

1

0

High-throughput

0.249

Low

1452110

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.249

Low

1047334

P
P protein

1

0

High-throughput

0.232

Low

1214205

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1227576

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1313862

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025