HitPredict

Interactor 1: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Interactor 2: Q8BNP7 (Q8BNP7)
Adenomatous polyposis coli protein
Gene: Apc

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	12874278, 20211142, 9554852, 15327768, 16611247
Identification Methods	two hybrid, affinity chromatography technology, pull down, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	APC_15aa~Arm, APC_rep~Arm, Arm~Arm
Common GO terms	GO:0005737 - cytoplasm GO:0071944 - cell periphery
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 781 Mm			1 1056
+	Rn
		1000466 CTNB1_RAT (1-781): 0: 643: 99.87		APC_RAT (1-1056): 0: 1656: 96.21
+	Hs
		668517 CTNB1_HUMAN (1-781): 0: 643: 99.87		APC_HUMAN (1-1056): 0: 1621: 95.09
+	Hs
		577621 PLAK_HUMAN (7-755): 3.55e-158: 479: 66.89		APC_HUMAN (1-1056): 0: 1621: 95.09
+	Hs
		353765 CTNB1_HUMAN (1-781): 0: 643: 99.87		APCL_HUMAN (2-979): 0: 1242: 49.95
+	Dm
		616590 ARM_DROME (11-780): 1.02e-160: 489: 65.58		Q9VAS9_DROME (230-789): 0: 668: 47.73
+	Dm
		616695 ARM_DROME (11-780): 1.02e-160: 489: 65.58		Q9Y1T2_DROME (325-748): 1.67e-180: 556: 48.49
+	Dm
		616572 ARM_DROME (11-780): 1.02e-160: 489: 65.58		Q961B0_DROME (325-748): 4.77e-180: 555: 48.49
+	Ce
		232034 HMP2_CAEEL (89-662): 7.72e-125: 390: 34.16		APR1_CAEEL (272-766): 3.53e-157: 498: 27.78
+	Ce
		1166285 BAR1_CAEEL (129-705): 1.17e-96: 320: 25.52		APR1_CAEEL (272-766): 3.53e-157: 498: 27.78