HitPredict

Interactor 1: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Interactor 2: USP9X (Q93008)
Ubiquitin carboxyl-terminal hydrolase 9X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X)
Gene: USP9X

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23524849
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 618 Hs			1 2554
+	Hs
		1206014 MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		1035952 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		177706 BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12		USP9X_HUMAN (1-2554): 0: 3676: 100.00
+	Hs
		1036312 BIRC2_HUMAN (1-618): 0: 702: 100.00		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		1035953 BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		957762 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UBP47_HUMAN (1465-2053): 7.75e-108: 381: 19.49
+	Hs
		962847 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP48_HUMAN (1473-2056): 6.89e-105: 365: 20.75
+	Mm
		620848 MDM2_MOUSE (319-617): 5.64e-35: 140: 16.21		UBP7_MOUSE (1469-2119): 1.12e-95: 339: 18.82
+	Hs
		962832 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP51_HUMAN (1424-1931): 7.9e-100: 341: 15.84
+	Hs
		962904 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		957751 XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82
+	Hs
		259276 MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56		UBP12_HUMAN (1519-1957): 8.45e-94: 311: 21.51
+	Hs
		177733 BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12		UBP22_HUMAN (1505-1931): 1.76e-100: 336: 17.68
+	Hs
		1264871 RFFL_HUMAN (567-618): 2.51e-17: 85.8: 42.31		UBP7_HUMAN (1469-2119): 8.05e-96: 339: 18.82