Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1
Interactor 2: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.771 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25505069, 25939382, 29033244, 28416489, 28380357, 28617433, 28846113, 30126895, 30907226, 32296183, 31169361, 33397898, 35074488, 35123989, 36952345, 37219487, 19615732, 20421418, 20495340, 20378532 and 25 others
more... |
| Identification Methods | affinity chromatography technology, enzymatic study, two hybrid, unspecified method, pull down, proximity labelling technology, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array and 5 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
