HitPredict

Interactor 1: G5E9A7 (G5E9A7)
DM1 locus, WD repeat containing (Dystrophia myotonica-containing WD repeat motif, isoform CRA_a)
Gene: DMWD

Interactor 2: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 649 Hs			1 605
+	Hs
		271161 FBXW7_HUMAN (75-349): 1.76e-27: 120: 7.07		UBP2_HUMAN (1-605): 0: 636: 100.00
+	Hs
		905378 DMWD_HUMAN (16-649): 1.32e-123: 383: 96.21		UBP46_HUMAN (243-600): 1.24e-108: 332: 24.33
+	Hs
		259279 DMWD_HUMAN (16-649): 1.32e-123: 383: 96.21		UBP12_HUMAN (266-600): 3.85e-107: 329: 26.50
+	Hs
		905392 WDR20_HUMAN (9-635): 1.07e-118: 367: 53.17		UBP46_HUMAN (243-600): 1.24e-108: 332: 24.33
+	Hs
		259297 WDR20_HUMAN (9-635): 1.07e-118: 367: 53.17		UBP12_HUMAN (266-600): 3.85e-107: 329: 26.50
+	Ce
		90257 WDR20_CAEEL (13-647): 1.28e-83: 280: 32.66		UBP46_CAEEL (266-600): 1.8e-95: 300: 25.32
+	Hs
		103873 G5E9A7_HUMAN (16-649): 9.26e-130: 398: 100.00		UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92
+	Hs
		301377 DMWD_HUMAN (16-649): 1.32e-123: 383: 96.21		UBP19_HUMAN (454-602): 3.28e-23: 107: 39.62
+	Hs
		1281441 FBXW7_HUMAN (75-349): 1.76e-27: 120: 7.07		UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15
+	Hs
		1058326 FBW1A_HUMAN (314-647): 3.13e-29: 124: 15.68		UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96
+	Hs
		1058268 FBXW7_HUMAN (75-349): 1.76e-27: 120: 7.07		UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96
+	Hs
		197099 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15
+	Hs
		929462 RACK1_HUMAN (155-448): 1.06e-25: 110: 17.73		UBP10_HUMAN (94-600): 1.5e-102: 330: 18.96
+	Hs
		197036 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		UBP39_HUMAN (57-600): 3.42e-104: 327: 19.75
+	Hs
		1346960 NLE1_HUMAN (83-241): 2.52e-19: 93.3: 11.95		UBP36_HUMAN (162-598): 2.8e-102: 336: 27.15
+	Hs
		850187 SKI8_HUMAN (175-444): 1.4e-46: 168: 16.08		UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98
+	Hs
		1377162 FBW1A_HUMAN (314-647): 3.13e-29: 124: 15.68		UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92
+	Hs
		197111 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		UBP15_HUMAN (451-597): 1.6e-28: 123: 43.92
+	Hs
		849988 RACK1_HUMAN (155-448): 1.06e-25: 110: 17.73		UBP11_HUMAN (453-605): 5.32e-29: 124: 37.98
+	Hs
		197012 PRP4_HUMAN (354-642): 6.78e-25: 111: 12.33		UBP4_HUMAN (447-597): 2.22e-28: 122: 42.76