Protein: S38A2
Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2)

Gene: S38A2, SLC38A2
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q96QD8

Gene Ontology (top 5):
GO:0003333 - amino acid transmembrane transport
GO:0005283 - amino acid:sodium symporter activity
GO:0005295 - neutral L-amino acid:sodium symporter activity
GO:0005298 - proline:sodium symporter activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

851087

LPAR6
Lysophosphatidic acid receptor 6

2

2

High-throughput

0.628

High

967344

TSN5
Tetraspanin-5

2

8

High-throughput

0.628

High

955493

CDC42
Cell division control protein 42 homolog

2

20

High-throughput

0.611

High

1400536

TM237
Transmembrane protein 237

2

1

High-throughput

0.606

High

869956

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

2

3

High-throughput

0.601

High

845765

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

1004168

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.586

High

218650

TGON2
Trans-Golgi network integral membrane protein 2

2

3

High-throughput

0.584

High

375852

RASK
GTPase KRas

2

12

High-throughput

0.584

High

540629

LAMP1
Lysosome-associated membrane glycoprotein 1

2

7

High-throughput

0.584

High

978234

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

1400736

DCDC2
Doublecortin domain-containing protein 2

2

0

High-throughput

0.580

High

286711

STX11
Syntaxin-11

1

4

High-throughput

0.541

High

164957

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

3

High-throughput

0.536

High

706048

CXB2
Gap junction beta-2 protein

1

7

High-throughput

0.536

High

1212287

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.536

High

1400605

KI20B
Kinesin-like protein KIF20B

1

1

High-throughput

0.536

High

1400718

RNF5
E3 ubiquitin-protein ligase RNF5

1

2

Small-scale

0.536

High

1400723

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.536

High

292724

RENR
Renin receptor

1

0

High-throughput

0.513

High

1010093

DLK1
Protein delta homolog 1

1

0

High-throughput

0.513

High

1383953

DACT3
Dapper homolog 3

1

0

High-throughput

0.513

High

1390513

P3IP1
Phosphoinositide-3-kinase-interacting protein 1

1

0

High-throughput

0.513

High

422942

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

298780

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

2

High-throughput

0.489

High

617575

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

2

High-throughput

0.489

High

699027

CALX
Calnexin

1

2

High-throughput

0.489

High

940620

ATP5E
ATP synthase F(1) complex subunit epsilon, mitochondrial

1

5

High-throughput

0.489

High

1382159

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.489

High

125573

LEG9
Galectin-9

1

6

High-throughput

0.479

High

126752

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

189782

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

226175

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

299339

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

341126

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

374146

RASN
GTPase NRas

1

12

High-throughput

0.479

High

374862

RASH
GTPase HRas

1

8

High-throughput

0.479

High

404346

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

414446

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

463713

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

466421

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

562332

LAMP2
Lysosome-associated membrane glycoprotein 2

1

7

High-throughput

0.479

High

581239

RAC2
Ras-related C3 botulinum toxin substrate 2

1

19

High-throughput

0.479

High

601408

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

604160

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

630612

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.479

High

631421

RAB5A
Ras-related protein Rab-5A

1

6

High-throughput

0.479

High

715726

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

827250

ARL1
ADP-ribosylation factor-like protein 1

1

5

High-throughput

0.479

High

900994

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.479

High

901503

RAB7A
Ras-related protein Rab-7a

1

8

High-throughput

0.479

High

902016

RAB9A
Ras-related protein Rab-9A

1

6

High-throughput

0.479

High

910169

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

936417

AFAD
Afadin

1

2

High-throughput

0.479

High

941832

ARL4C
ADP-ribosylation factor-like protein 4C

1

8

High-throughput

0.479

High

953622

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

962399

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

966772

1433G
14-3-3 protein gamma

1

1

High-throughput

0.479

High

975187

ARF6
ADP-ribosylation factor 6

1

3

High-throughput

0.479

High

988625

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1015691

RHOG
Rho-related GTP-binding protein RhoG

1

19

High-throughput

0.479

High

1041234

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1049689

1433F
14-3-3 protein eta

1

1

High-throughput

0.479

High

1087248

STX4
Syntaxin-4

1

4

High-throughput

0.479

High

1145065

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

1146459

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

1151825

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1159807

OCLN
Occludin

1

1

High-throughput

0.479

High

1163400

CAH9
Carbonic anhydrase 9

1

2

High-throughput

0.479

High

1197678

MIDN
Midnolin

1

1

High-throughput

0.479

High

1233430

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1249133

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1255141

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1270952

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1286875

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.479

High

1322954

CXD3
Gap junction delta-3 protein

1

7

High-throughput

0.479

High

1333961

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1366865

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1396615

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

1400724

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1400725

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1400727

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1400731

ELOV5
Very long chain fatty acid elongase 5

1

4

High-throughput

0.479

High

1400735

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1400737

LAMP3
Lysosome-associated membrane glycoprotein 3

1

7

High-throughput

0.479

High

1400739

ARL5A
ADP-ribosylation factor-like protein 5A

1

6

High-throughput

0.479

High

178367

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

580675

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

582928

EZRI
Ezrin

1

0

High-throughput

0.458

High

1107120

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1108060

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1135367

SLMAP
Sarcolemmal membrane-associated protein

1

0

High-throughput

0.458

High

1353248

PARD3
Partitioning defective 3 homolog

1

0

High-throughput

0.458

High

1400720

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1400722

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

1400728

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1400729

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

443929

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.445

High

872004

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

2

High-throughput

0.445

High

954233

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.445

High

983031

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.445

High

1006166

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

2

High-throughput

0.445

High

1257807

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.445

High

1316352

AGRG5
Adhesion G-protein coupled receptor G5

1

1

High-throughput

0.445

High

1349215

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

2

High-throughput

0.445

High

139964

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

174057

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.437

High

180022

BET1
BET1 homolog

1

6

High-throughput

0.437

High

327415

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

519198

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.437

High

630940

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.437

High

768939

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

880651

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.437

High

956451

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.437

High

976496

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.437

High

1293116

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

1314533

TM192
Transmembrane protein 192

1

1

High-throughput

0.437

High

1368936

GOGA1
Golgin subfamily A member 1

1

2

High-throughput

0.437

High

1381492

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

3

High-throughput

0.437

High

1381937

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1400717

SEC62
Translocation protein SEC62

1

1

High-throughput

0.437

High

1400721

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1400732

TM216
Transmembrane protein 216

1

1

High-throughput

0.437

High

1400733

ANFY1
Rabankyrin-5

1

1

High-throughput

0.437

High

1400734

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

1400740

SAR1B
Small COPII coat GTPase SAR1B

1

6

High-throughput

0.437

High

168891

PLD2
Phospholipase D2

1

0

High-throughput

0.426

High

428486

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.426

High

785378

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.426

High

859031

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.426

High

860326

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.426

High

970049

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.426

High

972752

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.426

High

1034048

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.426

High

299679

ATP5L
ATP synthase F(0) complex subunit g, mitochondrial

1

1

High-throughput

0.407

High

665675

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

2

High-throughput

0.407

High

940683

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

2

High-throughput

0.407

High

961563

VA0D1
V-type proton ATPase subunit d 1

1

2

High-throughput

0.407

High

1217951

AT5EL
ATP synthase subunit epsilon-like protein, mitochondrial

1

5

High-throughput

0.407

High

1329389

TEX29
Testis-expressed protein 29

1

0

High-throughput

0.279

Low

1400730

TM140
Transmembrane protein 140

1

0

High-throughput

0.279

Low

1400738

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

417691

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

589459

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696262

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

951364

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

1229634

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1238785

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

1400719

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

1400726

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

256959

H2B1K
Histone H2B type 1-K

1

0

High-throughput

0.232

Low

829504

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

935953

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025