HitPredict

Interactor 1: MED21 (Q13503)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7) (hSrb7)
Gene: MED21

Interactor 2: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	33961781, 28514442, 24981860, 35271311, 23602568
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 502
+	Hs
		826268 MED21_HUMAN (1-144): 1.5e-69: 207: 100.00		CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69
+	Hs
		73027 MED21_HUMAN (1-144): 1.5e-69: 207: 100.00		B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00
+	Hs
		841190 MED21_HUMAN (1-144): 1.5e-69: 207: 100.00		CDK7_HUMAN (27-354): 7.4e-56: 191: 38.21