Interactor 1: TRPC3 (Q13507)
Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (TRP-3) (hTrp-3) (hTrp3)
Gene: TRPC3

Interactor 2: TRPC7 (Q9HCX4)
Short transient receptor potential channel 7 (TrpC7) (Transient receptor protein 7) (TRP-7) (hTRP7)
Gene: TRPC7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 12032305, 33961781
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~TRP_2, Ion_trans~Ion_trans
Common GO terms GO:0005262 - calcium channel activity
GO:0005886 - plasma membrane
GO:0007338 - single fertilization
GO:0015279 - store-operated calcium channel activity
GO:0034703 - cation channel complex
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 921
Hs

1 862
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Last updated: 15 Jul 2024